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  3. PhD student / Post-doctoral Researcher in Genetics of Cardiac Disorders

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PhD student / Post-doctoral Researcher in Genetics of Cardiac Disorders

We have a vacancy for a PhD candidate or Post-doc to join our Cardiac Genetics group at the Academic Medical Center in Amsterdam. Our young and ambitious team conducts large international studies on patients with ...

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Arbeidsvoorwaarden

Standplaats:
Meibergdreef, Amsterdam, Noord-Holland
Dienstverband:
Tijdelijk contract / Tijdelijke opdracht
Uren per week:
36 uur
Opleidingsniveau:
WO

Functieomschrijving

We have a vacancy for a PhD candidate or Post-doc to join our Cardiac Genetics group at the Academic Medical Center in Amsterdam. Our young and ambitious team conducts large international studies on patients with rare cardiac disorders for the identification of genetic variation predisposing to sudden cardiac death. Our team is multidisciplinary, with expertise in clinical cardiology, clinical genetics, molecular genetics, biostatistics as well as disease modeling in cellular systems and mice.

The successful applicant will construct and manage large international databases and related DNA biobanks of patients with inherited cardiac disorders. By means of these databases he/she will combine clinical data with large-scale genetic data obtained by genomewide array genotyping, whole exome sequencing and whole genome sequencing for the identification of genetic factors contributing to cardiac disease and susceptibility to sudden cardiac death. These large genetic data sets are generated in the context of projects funded by NWO (VICI), H2020 and the Netherlands Heart Foundation. The successful applicant will be expected to develop novel ideas, apply them to the analysis of the data and interpret the emerging results. He/she will be actively involved in discussing and prioritizing genes emerging from the analysis for functional studies in cellular systems or mice that will be conducted by other members of the team.

Functie-eisen

  • You have a MSc or PhD degree in Medicine, Medical Biology or Biomedical Sciences
  • You are preferably proficient in statistical programming languages and statistical analysis methods (eg. R)
  • You are flexible and can handle different projects concurrently
  • You are a team player that shares knowledge and skills with colleagues
  • You are independent and have organizational skills
  • You have excellent written and verbal communication skills
  • Fluent in English (written and spoken)

Conditions

We offer a fixed term contract for 36 hours per week for 1 year, starting preferably before mid-2018, which under normal circumstances will be prolonged with 2 (for Post-doc) or 3 years (for PhD student). The salary is in accordance with the description of salary for a PhD student / post-doctoral researcher in the CAO-UMC.

A PhD student (Onderzoeker in Opleiding) is placed in scale 21, with a fulltime gross salary that ranges from €2279,- to €2919,- (based on qualifications and experience).

For a doctor (Arts-Onderzoeker) or Postdoctoral Researcher it’s scale 10, with a fulltime gross salary that ranges from €2919,- to €4216,- (based on qualifications and experience).

The applicant will get a contract through the AMC Medical Research BV, which includes a payment of holiday allowance of 8% and a year-end bonus of 8.3% of the gross annual salary.

Additional information

For more information, please contact Prof. Dr. C.R. Bezzina by email (c.r.bezzina@amc.uva.nl) or phone (020-5665403)

Bedrijfsomschrijving

The AMC is more than just a hospital. It is a world in which patient care, research and education are integrated, and in which people are always central. It is an academic world full of possibilities for talented individuals that are looking for a place where they can excel. Thinking big, daring to dream, cooperating internationally. And never letting yourself be put off by ‘It’s not possible’ or ’It won’t work anyway’. That is the AMC mentality.

The department of Experimental Cardiology is a research laboratory consisting of 5 groups each led by a group leader / principal investigator. The department has a long-standing tradition of research on cardiac arrhythmias that cause sudden cardiac death. The department is an integral part of the ‘Hartcentrum’ of the AMC, which means that researchers are connected to the Clinical Cardiology department, which stimulates translational research that benefits patients suffering from life-threatening cardiac diseases.