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PhD Position

Multipartite viruses have two or more genome segments, packaged individually into virus particles. This virus-particle organization should have major drawbacks for infection efficiency, but surprisingly multipartite viruses are nevertheless common among plant viruses. The frequency ...

7 months

Arbeidsvoorwaarden

Standplaats:
Droevendaalsesteeg, Wageningen, Gelderland
Dienstverband:
Tijdelijk contract / Tijdelijke opdracht
Uren per week:
38 uur
Salarisindicatie:
€ 2174 - € 2779 per maand
Opleidingsniveau:
WO

Functieomschrijving

Multipartite viruses have two or more genome segments, packaged individually into virus particles. This virus-particle organization should have major drawbacks for infection efficiency, but surprisingly multipartite viruses are nevertheless common among plant viruses. The frequency of these different segments can vary, but appears to converge on a host-species-dependent equilibrium. As part of the NWO VIDI project of Dr. Mark P. Zwart on the evolution of multipartite viruses, we want to use experimental evolution to study how resistant this equilibrium is to perturbations. We also want to know what role variation in genome segment frequencies plays in adaptation to new environments, and how it affects the expression of virus and host genes. This project will be a close collaboration with Wageningen University, in particular with Prof. Dr.ir. René van der Vlugt and Prof. Dr. Monique van Oers (Laboratory of Virology) and Prof. Dr. Arjan de Visser (Laboratory of Genetics).

Functie-eisen

  • MSc degree in virology, microbiology, evolutionary biology or a closely related field

  • The ideal candidate will have demonstrable experience with both (plant) viruses and evolution

  • Highly motivated candidate with creative, critical and conceptual thinking skills

  • Experience with molecular methods

  • Good communication skills in English (written and spoken) and the ability to work in a team are essential

Conditions

The gross salary starts at € 2.174, - per month in the 1st year, and will gradually increase to a maximum of € 2.779, - per month in the 4th year, scale P, Collective Agreement for Dutch Universities (CAO Nederlandse Universiteiten), excluding 8% holiday pay and a year-endbonus.

Additional information

Appointment: This is a temporary appointment, initially for 1 year and upon satisfaction to be prolonged for a maximum of 4 years (1fte) or 5 years(0.8fte).

Starting day: March/April 2018

Additional information is available upon request from Dr. Mark Zwart m.zwart@nioo.knaw.nl tel:+31 (0317)-473431. Information on NIOO-KNAW can be found on the Internet: http://www.nioo.knaw.nl

Bedrijfsomschrijving

The Netherlands Institute of Ecology (NIOO-KNAW) is a top research institute of the Royal Netherlands Academy of Arts and Sciences (KNAW). NIOO-KNAW focuses on fundamental and strategic research on individual organisms, populations, communities, and ecosystems.