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  3. Assistant or Associate Professor in Cellular Immunotherapy

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Assistant or Associate Professor in Cellular Immunotherapy

As a member of an enthusiastic group of dedicated researchers and clinicians, you will strengthen the major research & development program of the LUMC Department of Hematology. The team focuses primarily on developing efficient and specific cellular immunotherapeutic strategies as precision medicine for hematological malignancies and pursues the potential for malignant diseases in general.

ongeveer 2 maanden geleden

Arbeidsvoorwaarden

Standplaats:
Albinusdreef, Leiden, Zuid-Holland
Dienstverband:
Tijdelijk contract / Tijdelijke opdracht
Uren per week:
36 uur
Opleidingsniveau:
Postdoctoraal

Functieomschrijving

You will be responsible for cellular therapeutic strategies that are applied at the LUMC Department of Hematology. This task primarily involves GMP production of ATMPs that are developed by scientists and clinicians within the Department of Hematology itself or in the context of national or European consortia. Currently, we have a leading role in an ongoing EU clinical trial in which patients after allogeneic stem cell transplantation (allo-SCT) are treated with multi-virus specific donor T cells. In addition, a TCR gene therapy in which patients after allo-SCT are treated with donor T cells genetically modified with a hematopoiesis-specific TCR has started patient recruitment in July 2020, and a TCR gene therapy for mutant NPM1 will be implemented in our clinic in the coming year. Furthermore, the Department is the sole institution in The Netherlands holding a hospital exemption to generate and administer virus-specific T cells to treat patients with refractory CMV disease as advanced routine medical care. Finally, you will have the possibility to establish, develop and head your own research group in the field of immunology/hematology, thereby complementing the current research program of the department.

In short

·       You will lead the intradepartmental laboratory for the preclinical development of advanced therapy medicinal products (ATMPs) according to Good Manufacturing Practice (GMP)

·       You will supervise the actual production of ATMP for patients participating in several investigator-initiated clinical trials

·       You will actively participate in investigator-initiated studies on novel cellular interventions

·       You will be facilitated to establish, develop and head your own research group

·       You will be active in attracting external funding

·       You will collaborate with companies and other institutes (national and international) to develop novel cellular therapies.

Functie-eisen

You have a doctorate degree with a proven track record in immunology, hematology or immunotherapy with a strong desire to translate experimental findings into clinical therapies.

Conditions

Your salary is based on experience and conform CAO UMC.

Additional information

Your career at the LUMC

The LUMC helps you with maintaining and developing your knowledge and expertise. We offer internal courses and in-service training to assist you with your personal development. We also offer services in terms of personal development, mobility and career advice.

More information

The position starts on November 1st, 2020.

You can also contact Mirjam Heemskerk, associate professor at the Department of Hematology, telephone +31(0)71 526 32 07 / 526 22 71.

Contact details: Hendrik Veelken, Head of the Department of Hematology, telephone +31(0)71 526 22 67.