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PhD Candidate Cancer Immunotherapy

Are you interested in an interesting PhD opportunity? We are looking for a candidate who will become part of an international team doing basic and translational research aimed to improve cancer immunotherapy.

6 maanden geleden

Arbeidsvoorwaarden

Standplaats:
Albinusdreef, Leiden, Zuid-Holland
Dienstverband:
Tijdelijk contract / Tijdelijke opdracht
Uren per week:
36 uur
Salarisindicatie:
€ 2422 - € 3103 per maand
Opleidingsniveau:
WO

Functieomschrijving

In our group, we aim to understand the molecular and cellular requirements for optimal anti-tumor T cell responses. Your project concerns delineating key signaling pathways for optimal function in T cells and dendritic cells in vivo in mouse models, and matching mouse and human cellular systems in vitro. We collaborate with the ‘clinic’, and we aim to translate immunotherapy-assisted vaccination strategies to application in cancer patients. Techniques include: in vivo mouse work, flow cytometric and functional analyses of immune cells, genome-wide transcriptomic and epigenetic analyses and associated bioinformatics, and molecular biology including CRISPR/Cas9-mediated gene editing.

Functie-eisen

We are looking for an enthusiastic and ambitious PhD student, with a university master’s degree and a background in immunology and cell biology. You have affinity with mouse studies and a motivation to understand biological systems at the molecular level. ‘Article 9’ competence is advantageous. Fluency in spoken and written English is a requirement.

Conditions

You will work 36 hours per week. You will be appointed for the duration of your studies, to be finished with a doctoral thesis, and for a maximum of four years. Your salary is a maximum of € 2,422 gross per month in the first year amounting to a maximum of € 3,103 gross per month in the final year, based on a fulltime position (scale Pro of the collective labor agreement of the University Medical Centers).

Additional information

Contact: Prof. Jannie Borst, professor and head of the Department IHB, telephone: +31(0)71 526 19 70; email: j.g.borst@lumc.nl.