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PhD Candidate Early Detection of Pulmonary Hypertension

Pulmonary hypertension, or increase in pulmonary blood pressure, is a fatal condition since there are no known effective interventions to reverse pulmonary vascular remodelling or to prevent right heart failure. Early detection of the patient at risk as well as identifying the right drug for the right patient are important to halt and reverse the disease. We are looking for a PhD candidate to help us with research on this topic.

2 maanden geleden


Albinusdreef, Leiden, Zuid-Holland
Tijdelijk contract / Tijdelijke opdracht
Uren per week:
36 uur
€ 2495 - € 3196 per maand


As a PhD candidate you will be working within the CVON-DOLPHIN consortium which focus on the development of methods for early detection of pulmonary hypertension in genetically susceptible individuals. You will develop a toolbox to identify vascular vulnerability and pulmonary arterial hypertension development in mutation carriers.

In short

· You will work within the CVON-DOLPHIN consortium

· You will be part of a multidisciplinary team in an innovative academic environment

· You will develop a toolbox to identify vascular vulnerability and pulmonary arterial hypertension development in mutation carriers

· With this research you aim to obtain your PhD degree


We seek a highly motivated and enthusiastic candidate who can work independently and is creative in seeking solutions when encountering problems. You have an MSc degree in molecular biology, genetics, biochemistry or a closely related discipline. You have experience with cell culture and RNA/protein analyses. Knowledge of metabolomics, exosomes and CyTOF is advantageous. You have excellent organizational skills and the capacity to work and communicate in a multidisciplinary team. You have a flexible mindset and the motivation to work on multiple projects simultaneously.


You will be employed on the basis of 36 hours per week. Appointment is for a maximum of four years, to be completed with a doctoral thesis. Your salary will start with € 2,495 gross per month in the first year, amounting to a maximum of € 3,196 gross per month in the fourth year based on a fulltime position (scale for PhD students in the Collective Labour Agreement for University Hospitals).

Additional information

Career at the LUMC

The LUMC helps you with maintaining and developing your knowledge and expertise. We offer internal courses and in-service training to assist you with your personal development. We also offer services in terms of personal development, mobility and career advice.

Contact: Marie-José Goumans, professor, Department of Cell and Chemical Biology, telephone +31(0)71 526 92 77.