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PhD Candidate Influences of Gender in Pulmonary Arterial Hypertension

Pulmonary hypertension, or increase in pulmonary blood pressure, is a fatal condition since there are no known effective interventions to reverse pulmonary vascular remodelling or to prevent right heart failure. Early detection of the patient at risk as well as identifying the right drug for the right patient are important to halt and reverse the disease. We are looking for a PhD candidate to help us with research on this topic.

2 maanden geleden


Albinusdreef, Leiden, Zuid-Holland
Tijdelijk contract / Tijdelijke opdracht
Uren per week:
36 uur
€ 2495 - € 3196 per maand


Within the PHAERA-IMPACT consortium we aim to identify different risk factors and modifiers that will determine the initiation and progression of pulmonary arterial hypertension. The aim of your PhD project is to understand how gender influences disease onset and penetrance. You will use patient derived cells as well as animal models to answer this question.

In short

· You will work within the PHAERA-IMPACT consortium

· You will be part of a multidisciplinary team in an innovative academic environment

· The focus in your research is on gender influences on disease and penetrance

· With this research you aim to obtain your PhD degree


We are looking for a PhD candidate who holds a master’s degree in the area of biomedical sciences, biology or pharmacy. You have experience with molecular and biochemical techniques, such as protein purification and western blot. You also have experience with cellular and immunological techniques, such as cell culture, FACS-analysis and ELISA. Experience with animal models and/or 3D cell culture models is advantageous. You should be able to work in a team as well as independently. You have a flexible mindset and the motivation to work on multiple projects simultaneously.


You will be employed on the basis of 36 hours per week. Appointment is for a maximum of four years, to be completed with a doctoral thesis. Your salary will start with € 2,495 gross per month in the first year, amounting to a maximum of € 3,196 gross per month in the fourth year based on a fulltime position (scale for PhD students in the Collective Labour Agreement for University Hospitals).

Additional information

Career at the LUMC

The LUMC helps you with maintaining and developing your knowledge and expertise. We offer internal courses and in-service training to assist you with your personal development. We also offer services in terms of personal development, mobility and career advice.

Contact: Marie-José Goumans, professor, Department of Cell and Chemical Biology, telephone +31(0)71 526 92 77.