Are you an ambitious candidate looking for a position as a postdoctoral researcher? Do you want to work on a project that investigates the influence of light- and feeding schedules on brain function in night- and day-active rodents? Then this is the position for you!
- Albinusdreef, Leiden, Zuid-Holland
- Tijdelijk contract / Tijdelijke opdracht
- Uren per week:
- 36 uur
- € 4481 per maand
Identifying and understanding the causal mechanisms that link circadian clock dysfunction with disease are key steps towards developing strategies to treat—or even prevent—clock-related health conditions. However, most of our current knowledge is based on studies in nocturnal animal models. This ERC-funded project will therefore investigate components of the circadian system affecting disease progression in night- as well as day-active murine species. We are interested how the circadian clock is modulating functional brain networks in health and disease with the goal to use interventions to restore healthy conditions. We will investigate how photic environment and feeding schedules can influence the balance between excitatory and inhibitory (E/I) neuronal activity and network function in different brain regions (SCN, hippocampus, cortex). The postdoctoral researcher will use multi-electrode (tetrode) recording as well as imaging of genetically encoded calcium indicators to study neural networks in vivo and ex vivo.
· You have a PhD degree in Neuroscience
· You have experience with in vivo electrophysiology
· You like to translate research findings to the clinic
· You are ambitious and a team player
You should have a PhD in Neuroscience, or in a related discipline, and rich hands-on experience in neurophysiological recording and analysis techniques. Experience with in vivo electrophysiology and/or imaging techniques is strongly preferred. Ideally, you must have demonstrated a strong interest in an academic career through your publication record and prior engagements in collaborative, multidisciplinary, research. This position requires a person who recognizes the benefits of access to the academic resources of two top-rated research institutes and the flexibility to adapt to different academic cultures. You will achieve this because you are an enthusiastic, motivated and flexible team player with excellent communicative skills in English. Working in these productive research teams will give you an excellent opportunity to build up your own network and develop your own research line.
The appointment is for 3 years. Your salary will depend on your qualifications and experience and will be maximal € 4.481,- pre-tax per month based on a full-time employment (Scale 10 CAO LUMC). The terms of employment offered by the LUMC are highly favorable. For example, you will receive 8% holiday remuneration, a year-end bonus, and a pension arrangement with the National Civil Pension Fund. Also, as employee of one of the University Hospitals in the Netherlands, you can benefit from our collective health insurance policy.