Ongeveer 20 uur geleden - Erasmus Universiteit Rotterdam - Rotterdam
Job description We are expanding our team of Business Information Management faculty members to complement our ongoing research into this increasingly …
Understanding the complex cis-regulatory grammar underlying cell and tissue identity is of great importance for stem cell research and regenerative medicine. …
Understanding the complex cis-regulatory grammar underlying cell and tissue identity is of great importance for stem cell research and regenerative medicine. However, due to the inherent complexity of gene regulatory networks, our understanding of how they shape complex phenotypes remains incomplete. The proposed PhD project is part of the recently funded Vidi project 'Inference of gene regulatory logic in metazoan development'. This project aims to determine conserved gene regulatory modules in early animal development using genome-wide gene regulatory network inference in a large collection of species.
As a PhD candidate you will combine state-of-the-art computational algorithms and large data sets with an evolutionary developmental biology approach to gain insight into the rules by which regulatory elements define cell identity and behaviour. You will work on inference of genome-scale regulatory networks from integration of large and diverse experimental data sets (RNA-seq, ATAC-seq, ChIP-seq). Your work will include method development as well as application to analyse gene regulatory networks in development across metazoan species. You will also have the opportunity to develop novel ideas and work on an independent project aligning with our research interests.
Experience with the following would be an advantage:
Are you interested in our excellent employment conditions?
Dr. Simon van Heeringen
Telefoon: +31 24 3610560
No commercial propositions please.