Functieomschrijving
We are looking to recruit a motivated and ambitious experimental biologist to join us at the Department of Molecular Biology, Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University, Nijmegen, Netherlands. This position is part of a research project, which aims to understand liver development for regenerative medicine and disease modelling.
As the successful applicant, you will be employed to study hepatocyte differentiation. The main aim is to define the intricate regulatory circuitries and transcription factor networks that lead to full maturation of hepatocytes from liver progenitor cells. In order to obtain a comprehensive overview, you will apply a system biology approach (including single-cell transcriptomics and epigenomic approaches) on two state-of-the-art liver models (human iPS cells and organoids). You will further study the key factors identified by gain-of-function and/or loss-of-function approaches. You will have the opportunity to develop novel ideas and work on additional independent projects that align with this research theme.
