Atherosclerosis, the underlying cause of the majority of cardiovascular diseases, is a lipid-driven inflammatory disease of the large arteries. Experimental …
Data Scientist / Bioinformatician
In the position we offer, you apply your programming skills to offer practical solutions for the application of complex data in patient diagnostics. You will establish, maintain and further optimize a data-analysis pipeline for glycomics ...
- Landelijk / geen vaste standplaats
- Tijdelijk contract / Tijdelijke opdracht
- Uren per week:
- 32 - 36 uur
In our Translational Metabolic Laboratory, multiple analytical techniques are applied in diagnostic screening for inborn errors of metabolism (IEM). However, with the introduction of high-resolution mass spectrometry instruments in clinical laboratories, we aim to innovate our diagnostic process by developing new holistic approaches starting with metabolomics- and glycomics-based analyses for IEM diagnostics. In these innovative diagnostic assays, challenges lie in the translation of big data to a clinically valuable result for the individual patient.
In the position we offer, you apply your programming skills to offer practical solutions for the application of complex data in patient diagnostics. You will establish, maintain and further optimize a data-analysis pipeline for glycomics, metabolomics and glycoproteomics data from sample to final (diagnostic) report. This includes further workflow automation, integration with the Laboratory Information Management system and reference database development. You will work in a challenging environment with sensitive patient data. The work is performed in close collaboration with laboratory specialists, laboratory technicians and statistical/chemometric experts and carried out under the supervision of a senior bio-informatician. In addition, you will work in close communication with bioinformaticians from the department of Human Genetics and laboratory information management system administrators.
- Highly motivated and ability to work in an interdisciplinary environment at the cutting edge of science;
- BSc or MSc in Molecular Sciences, Bioinformatics, Computer Science, Statistics or equivalent;
- Level HBO+ / WO;
- Experience with SQL, R or Matlab, and in one or more object-oriented programming languages (C#, VB.Net, C/C++, Java, etc.);
- Web development;
- Database development (MySQL);
- You are a team player with good communicational skills, able to work in a laboratory with international eminence;
- You recognise yourself in the Radboud way of working.
Scale 8: max. € 46139 gross income per year at full employment (incl. vacation bonus and end of year payments).
Upon commencement of employment we require a certificate of conduct (Verklaring Omtrent het Gedrag, VOG). Radboud university medical center’s HR Department will apply for this certificate on your behalf.
All additional information about the vacancy can be obtained from Dr. Karlien Coene, clinical chemist, Dr. Leo Kluijtmans, clinical biochemical geneticist or Prof. Alain van Gool, head Translational Metabolic Laboratory, +31 (0)24 361 45 67. Use the Apply button to submit your application.
Radboudumc strives to be a leading developer of sustainable, innovative and affordable healthcare to improve the health and wellbeing of people and society in the Netherlands and beyond. This is the core of our mission: To have a significant impact on healthcare. To get a better picture of what this entails, check out our strategy film.
Our key strength is medical life-sciences and clinical practice, with an impressive infrastructure comprising state-of-the-art technology platforms and (translational) research facilities. The Radboudumc is therefore uniquely positioned in the emerging Euregio and Dutch healthcare infrastructure to play a leading role in the new healthcare paradigm of prediction, prevention and personalised medicine.
The Radboudumc focuses on scientific health challenges of today, with an eye on emerging diseases of the future.
Read more about what it means to work at Radboudumc and how you can do your part.
The Translational Metabolic Laboratory
The experimental research for the project is housed in the Translational Metabolic Laboratory (TML), which is part of the Department of Laboratory Medicine. The laboratory is a mixed function laboratory with patient care and translational research. The laboratory houses the Radboud Technology Center Mass Spectrometry. TML harbors a range of top researchers in the areas of inherited (metabolic) diseases, disorders of movement, mitochondrial disease, protein glycosylation and more. Click here for more information about TML.