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PhD candidate 'Cardiac CT perfusion imaging in acute chest pain'

Cardiac CT perfusion imaging in acute chest painMyocardial infarction and ischemia is a very common and important cause of mortality and morbidity worldwide. …

3 maanden geleden


Geert Grooteplein Zuid, Nijmegen, Gelderland
Tijdelijk contract / Tijdelijke opdracht
Uren per week:
36 - 36 uur
€ 3020 - € 3176 per maand


Cardiac CT perfusion imaging in acute chest pain
Myocardial infarction and ischemia is a very common and important cause of mortality and morbidity worldwide. To prevent these potential life-threatening consequences early detection of coronary artery disease is crucial. Nowadays, several non-invasive imaging techniques are available for early detection of coronary artery disease and cardiac ischemia.

Cardiac CT angiography and perfusion are imaging techniques that (1) combine both anatomical and functional information, and (2) are relatively widely available in the emergency setting. Cardiac CT angiography (CTA) depicts the coronary artery anatomy and pathology (coronary plaques/stenosis) while cardiac CT perfusion (CTP) can reveal cardiac ischemia on a segment basis. Combining cardiac CTA and CTP has been shown to result in good accuracy for diagnosis of cardiac ischemia. Besides their evident diagnostic value, cardiac CTA and CTP can guide therapeutic decisions: i.e., the use of conservative vs. invasive treatment.

In this PhD project, you will perform a clinical implementation study using cardiac CTP in patients with acute chest pain in the emergency department. During this study, the information from cardiac CTA and CTP will be used to determine if the patient can be discharged from the emergency department or has to be admitted to the hospital for further invasive workup/treatment. Besides clinical relevant outcome parameters, this study aims to optimize the CTP acquisition protocol with special attention for radiation dose and image quality.

Throughout the project you will collaborate closely with (cardiovascular) radiologists, cardiologists, CT radiographers, and physicists, as well as be a member of the AXTI lab team.


  • You should be a creative, enthusiastic and ambitious researcher with an academic degree as Doctor in Medicine (M.D.);
  • Team player with good communication skills;
  • Experience or interest in (cardiovascular) imaging;
  • Excellent communication skills in English, both written and spoken;
  • Written en spoken Dutch required.


Upon commencement of employment we require a certificate of conduct (Verklaring Omtrent het Gedrag, VOG) and there will be, depending on the type of job, a screening based on the provided cv. Radboud university medical center's HR Department will apply for this certificate on your behalf.

Read more about the Radboudumc employment conditions and what our International Office can do for you when moving to the Netherlands.

Additional information

The following should be included in your application: cv, list of completed courses and grades, a letter of motivation, and reprints or, preferably, links to your thesis or any scientific publications or reports in English that you have written.

All additional information about the vacancy can be obtained from Dr. Jesse Habets, Radiologist and Dr. Ioannis Schechopoulos, associate professor. Use the Apply button to submit your application.

Please apply before 13 March.
Recruitment agencies are asked not to respond to this job posting.