Postdoc 'Identification and understanding genetic modifiers of hereditary hearing loss'

Functieomschrijving

We are looking for a postdoc for our research within Hearing & Genes. Our research is directed towards the identification and understanding the genetic causes of hearing loss and the development of (genetic) therapies using cell and animal models (zebrafish, mice). Will you join us?

Long ago, Helen Keller indicated "Blindness separates people from things; deafness separates people from people." Hearing loss (deafness) is the most common sensory disorder in humans and is often due to genetic defects. We found that a specific defect in the RIPOR2 gene is an important cause of hearing loss (type DFNA21). This type of hearing loss is highly variable and genetic factors are indicated to contribute importantly to this variation.

The postdoc we are recruiting will be central in the identification of these modifying genetic factors. Such factors might well inform us on how to prevent the onset of hearing loss and/or on the design of therapeutic strategies. You will be part of the Hearing & Genes expert center for hereditary hearing loss.

Tasks and responsibilities

• Plan and perform scientific data analysis and experiments in an independent manner.
• Critically analyze results.
• Co-supervise junior scientists (technicians, MSc/BSc students).
• Take a leading role in writing manuscripts.
• Present data at local, national and international scientific meetings.
• Participate in educational tasks (optional).

Functie-eisen

Candidates must have obtained their PhD degree in the last three years (or submitted their thesis to the manuscript committee), in the field of molecular genetics or bioinformatics. A background in analysis of exome or genome sequencing data is required. Knowledge of gene regulatory elements, an experimental background or interest in experimental molecular (genetic) research, including DNA or RNA analysis, is preferred.

In addition, you should have strong communication skills (both orally and in writing), a critical scientific attitude, and a high level of ambition. You are able to work both independently as well as in a team.

Conditions

Anticipated start date: May 2022. Working at Radboud university medical center means that you are ahead of the curve and working together on the healthcare of the future. And there is more. Our secondary terms of employment are impressive. These are fully tailored to you thanks to our Employment Conditions Selection Model. At Radboud university medical center, you will be given trust, and you will take the responsibility to handle everything together. We provide annual courses, both professional and personal.

• In addition to your monthly salary and an annual vacation allowance of 8%, you will receive an end-of-year bonus of 8.3%.
• If you work irregular hours, you will receive an allowance.
• As a full-time employee (36 hours per week), you are entitled to approximately 168 vacation hours (over 23 days) per year.
• Radboud university medical center pays 70% of the pension premium. You pay the rest of the premium with your gross salary.
• You get a discount on health insurance as well: you can take advantage of two group health insurance plans. UMC Zorgverzekering and CZ collectief.

In addition to our terms of employment, we also offer employees various other attractive facilities, such as childcare and sports facilities. Want to learn more? Take a look at the CAO UMC.

Additional information

All additional information about the vacancy can be obtained from Prof. dr. Hannie Kremer, Professor of Molecular Otogenetics. Use the Apply button to submit your application.