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Postdoc 'Small RNA pathways in virus-transmitting mosquitoes'

We are looking for a highly motivated postdoctoral scientist to study regulatory functions of piRNAs, using genome-wide tools including RNA seq and ChIP (chromatin immunoprecipitation)-seq. As experimental models, both mosquito cell lines and adult mosquitoes will be used.

19 dagen geleden

Arbeidsvoorwaarden

Standplaats:
Geert Grooteplein Zuid, Nijmegen, Gelderland
Dienstverband:
Tijdelijk contract / Tijdelijke opdracht
Uren per week:
36 uur
Opleidingsniveau:
Postdoctoraal

Functieomschrijving

Mosquitoes are vectors for transmission of important human pathogens, such as Dengue virus, Zika virus and Chikungunya virus. Arboviruses are targeted by two small RNA pathways in the mosquito vector, the small interfering RNA pathway and the PIWI-interacting RNA (piRNA) pathway. In addition, the piRNA pathway seems to have additional functions in transposon control and gene regulation. Although siRNAs are well-studied, the biogenesis, mechanisms, and functions of piRNAs are not well understood.

For a project funded by a VICI grant from the Netherlands Organization for Scientific Research (NWO), we we are looking for a highly motivated postdoctoral scientist to study regulatory functions of piRNAs, using genome-wide tools including RNA seq and ChIP (chromatin immunoprecipitation)-seq. As experimental models, both mosquito cell lines and adult mosquitoes will be used.

Functie-eisen

  • Recent PhD degree in molecular biology;
  • Good track record of scientific publications;
  • Experience with next generation sequencing (RNA seq and/or ChIP seq) and analyses thereof;
  • Excellent communication skills and good command of spoken and written English;
  • Highly motivated to do fundamental scientific research;
  • You recognise yourself in the Radboud way of working.

Conditions

Scale 10: max. € 58838 gross income per year at full employment (incl. vacation bonus and end of year payments)

Read more about the Radboudumc employment conditions.

Additional information

All additional information about the vacancy can be obtained from Dr. Ronald van Rij, associate professor and head of the laboratory of Experimental Virology. Use the Apply button to submit your application.

Applicants should write a letter outlining specific interests in the position, experience and career goals, a curriculum vitae and contact information of two professional references.

Upon commencement of employment we require a certificate of conduct (Verklaring Omtrent het Gedrag, VOG) and there will be a screening based on the provided CV. Radboud university medical center’s HR Department will apply for this certificate on your behalf.