PhD Candidate for the Project “Moving Animals: A History of Science, Media and Policy in the Twentieth Century””
Ongeveer 6 uur geleden - Universiteit Maastricht - Maastricht
Mosquitoes are vectors for transmission of important human pathogens, such as Dengue virus, Zika virus and Chikungunya virus. Arboviruses are targeted by two …
Mosquitoes are vectors for transmission of important human pathogens, such as Dengue virus, Zika virus and Chikungunya virus. Arboviruses are targeted by two small RNA pathways in the mosquito vector, the small interfering RNA pathway and the PIWI-interacting RNA (piRNA) pathway. In addition, the piRNA pathway seems to have additional functions in transposon control and gene regulation. Although siRNAs are well-studied, the biogenesis, mechanisms, and functions of piRNAs are not well understood.
For a project funded by a VICI grant from the Netherlands Organization for Scientific Research (NWO), we we are looking for a highly motivated postdoctoral scientist to study regulatory functions of piRNAs, using genome-wide tools including RNA seq and ChIP (chromatin immunoprecipitation)-seq. As experimental models, both mosquito cell lines and adult mosquitoes will be used.