Postdoc 'Small RNA pathways in virus-transmitting mosquitoes'

Mosquitoes are vectors for transmission of important human pathogens, such as Dengue virus, Zika virus and Chikungunya virus. Arboviruses are targeted by two …

29 days

Arbeidsvoorwaarden

Standplaats:
Geert Grooteplein Zuid, Nijmegen, Gelderland
Dienstverband:
Tijdelijk contract / Tijdelijke opdracht
Uren per week:
36 - 36 uur
Salarisindicatie:
€ 2659 - € 4216 per maand
Opleidingsniveau:
Postdoctoraal

Functieomschrijving

Mosquitoes are vectors for transmission of important human pathogens, such as Dengue virus, Zika virus and Chikungunya virus. Arboviruses are targeted by two small RNA pathways in the mosquito vector, the small interfering RNA pathway and the PIWI-interacting RNA (piRNA) pathway. In addition, the piRNA pathway seems to have additional functions in transposon control and gene regulation. Although siRNAs are well-studied, the biogenesis, mechanisms, and functions of piRNAs are not well understood.

For a project funded by a VICI grant from the Netherlands Organization for Scientific Research (NWO), we we are looking for a highly motivated postdoctoral scientist to study regulatory functions of piRNAs, using genome-wide tools including RNA seq and ChIP (chromatin immunoprecipitation)-seq. As experimental models, both mosquito cell lines and adult mosquitoes will be used.

Functie-eisen

  • Recent PhD degree in molecular biology;
  • Good track record of scientific publications;
  • Experience with next generation sequencing (RNA seq and/or ChIP seq) and analyses thereof;
  • Excellent communication skills and good command of spoken and written English;
  • Highly motivated to do fundamental scientific research.

Conditions

Upon commencement of employment we require a certificate of conduct (Verklaring Omtrent het Gedrag, VOG) and there will be a screening based on the provided CV. Radboud university medical center's HR Department will apply for this certificate on your behalf.

Read more about the Radboudumc employment conditions and what our International Office can do for you when moving to the Netherlands.

Additional information

Application
Applicants should write a letter outlining specific interests in the position, experience and career goals, a curriculum vitae and contact information of two professional references.

Information
All additional information about the vacancy can be obtained from Dr. Ronald van Rij, associate professor and head of the laboratory of Experimental Virology or visit Van Rijlab.Use the Apply button to submit your application.

Please apply before August 24.
Recruitment agencies are asked not to respond to this job posting.

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