Biological Chemistry PhD: Single-molecule enzymology with nanoprores (2.0 FTE)
Biological nanopores are an exciting new class of biosensors, which main practical application is in single-molecule sequencing and single-molecule analysis. We are looking for talented and motivated students that are willing to engage in a PhD program to study enzymes at the sin
- Broerstraat, Groningen, Groningen
- Tijdelijk contract / Tijdelijke opdracht
- Uren per week:
- 38 - 38 uur
- € 2972 - € 2972 per maand
Biological nanopores are an exciting new class of biosensors, which main practical application is in single-molecule sequencing and single-molecule analysis. We are looking for talented and motivated students that are willing to engage in a PhD program to study enzymes at the single molecule level.
Small enzymes will be immobilized inside a biological nanopore by various methods (e.g genetically, via disulfide bridge, by click chemistry or by non-covalent interactions). The conformational changes associated with catalysis will then be observed by the altered ionic flow through the nanopore.
- you have a Masters Degree in Chemistry, Chemical Biology, Biochemistry or Biotechnology or equivalent
- you have Expertise in molecular biology (recombinant DNA techniques, protein expression and purification), chemical modification of proteins or peptides, MD simulations will be an advantage, but not a limiting factor.
ConditionsWe offer you in accordance with the Collective Labour Agreement for Dutch Universities:
- a salary of € 2,325 gross per month in the first year, up to a maximum of € 2,972 gross per month in the fourth and final year
- a full-time position (1.0 FTE)
- a holiday allowance of 8% gross annual income
- an 8.3% end-of-the-year allowance
- minimum of 29 holidays and additional 12 holidays in case of full-time employment.
The preferred starting date is as soon as possible.
Additional informationDr Giovanni Maglia
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