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PhD on biomarkers of radiation-induced toxicity from advanced MR imaging

The research performed in this project concerns a strong collaboration between TU Delft, Holland PTC, Leiden UMC, and Erasmus MC. A key treatment modality of …

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Arbeidsvoorwaarden

Standplaats:
Lorentzweg, Delft, Zuid-Holland
Dienstverband:
Tijdelijk contract / Tijdelijke opdracht
Uren per week:
38 - 38 uur
Salarisindicatie:
€ 2325 - € 2972 per maand
Opleidingsniveau:
WO

Functieomschrijving

The research performed in this project concerns a strong collaboration between TU Delft, Holland PTC, Leiden UMC, and Erasmus MC.

A key treatment modality of brain tumours is radiotherapy. However, conventional radiotherapy can have a detrimental effect on the surrounding healthy tissue. Proton therapy is a promising new form of therapy that improves the preservation of the healthy tissue.

Advanced MRI techniques can quantify changes in brain tissue already very early after radiotherapy. The recruited PhD will develop new markers of radiation toxicity from MR perfusion and diffusion imaging. In particular, the research will focus on creating new MRI acquisition schemes and novel techniques to process the data (e.g. machine learning approaches). Enhanced information will be obtained from knowledge of the physical principles underlying MR image acquistion and the brain's vasculature.

The research especially targets brain tumor patients undergoing photon and proton radiotherapy.

The PhD candidate will be based at TU Delft. Simultaneously, we foresee that an important part of the research will take place in our partnering medical institutes.

The project is funded by Holland PTC. HollandPTC’s mission is to provide patients with the best proton therapy presently available, in a safe and welcoming environment, where they are treated with care and diligence. You will be part of the HollandPTC R&D program. Its mission is to prove the added value of proton therapy, which we do in cooperation with the national and international radiotherapy and oncology community.

Functie-eisen

We are looking for a talented and enthusiastic PhD candidate with an MSc degree in (applied) physics, mathematics, electrical engineering or a related subject. He/she must have an excellent knowledge of written and spoken English, and a top 20% ranking during his/her BSc and MSc. Experience with MRI and image processing is helpful. Good programming skills in MATLAB and C are a necessity. 

Conditions

TU Delft offers a customisable compensation package, a discount for health insurance and sport memberships, and a monthly work costs contribution. Flexible work schedules can be arranged. An International Children’s Centre offers childcare and an international primary school. Dual Career Services offers support to accompanying partners. Salary and benefits are in accordance with the Collective Labour Agreement for Dutch Universities.

As a PhD candidate you will be enrolled in the TU Delft Graduate School. TU Delft Graduate School provides an inspiring research environment; an excellent team of supervisors, academic staff and a mentor; and a Doctoral Education Programme aimed at developing your transferable, discipline-related and research skills. Please visit www.tudelft.nl/phd for more information.

Additional information

For more information about this position, please contact Dr. Frans Vos, phone: +31 (0)15-2787133, e-mail: f.m.vos@tudelft.nl. If you are interested in this position, please send the following information in English (pdf format only):

1) a letter of motivation,

2) a detailed CV (containing amongst others a list of publications, a summary of your MSc thesis),

3) the names and contact details of three references,

4) A certified copy of your BSc and MSc degree*

5) A certified copy of the transcript of records belonging to your BSc and MSc degree*

Please e-mail your application to Mrs. Annelies van Beek, secr-qi-tnw@tudelft.nl, referring to vacancy number TNWIP19-025. The position will close on 30 September 2019.

* If the documents are not written in Dutch, English, French or German: a certified translation is mandatory.