3 dagen geleden - Academic Medical Center (AMC) - Amsterdam
You will initiate emerging, cutting-edge genome modification technologies across the AMC/VUmc alliance, and advance our expertise in functional cancer genomics…
High spatial resolutions from single molecule emitters, cryogenic temperatures
The researcher will work in a team of experimentalists and theorists who share the common goal of imaging at the nanometre scale. She/he will work at the interface of the team designing, performing experiments, and developing modelling for data analysis. In order to achieve very high spatial resolutions from single molecule emitters, the wavefront of the light must not be disturbed by optical aberrations. In reality, such aberrations are always present, but only at our targeted high resolution at cryogenic temperatures do they play a crucial role. Therefore, the candidate will develop adaptive optics instrumentation and algorithms to measure the wavefront distortion and subsequently correct the distortions. We will use spatial light modulators to shape the wavefront.
The research will be performed at the Department of Imaging Physics in the Faculty of Applied Sciences at Delft University of Technology.
The candidate must hold an MSc degree in Physics. The candidate should have a background in experimental physics using high-end technical equipment and should have a track record of measuring, analysing, and comparing data to model predictions. Experience with microscopy, optics, fluorescence, and/or simulation packages is beneficial but not required.
Delft University of Technology (the TU Delft) is a multifaceted institution offering education and carrying out research in the technical sciences at an internationally recognised level. Education, research and design are strongly oriented towards applicability. The TU Delft develops technologies for future generations, focusing on sustainability, safety and economic vitality. At the TU Delft you will work in an environment where technical sciences and society converge. The TU Delft comprises eight faculties, unique laboratories, research institutes and schools.
The position is in the Department of Imaging Physics of the Faculty of Applied Sciences. This department performs cutting-edge research spanning the range from understanding the basic principles underlying imaging technology to automated image analysis.
The Quantitative Imaging (QI) group performs fundamental and applied research in sensing (imaging systems), processing, analysis, and interpretation of multi-dimensional images. The research is applied in three multidisciplinary programmes: medical image processing, biomolecular imaging (light and electron microscopy), and industrial imaging. These programmes are conducted in close collaboration with partners in academia (including several university medical centres), industry, and governmental research institutes.
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