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  3. PhD Position Computational Microscopy

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PhD Position Computational Microscopy

Do you want to be part of the team that might shift the obtainable resolution in an optical light microscope even further towards 1 nm?

2 maanden geleden

Arbeidsvoorwaarden

Standplaats:
Mekelweg, Delft, Zuid-Holland
Dienstverband:
Tijdelijk contract / Tijdelijke opdracht
Uren per week:
38 - 38 uur
Salarisindicatie:
€ 2395 - € 3061 per maand
Opleidingsniveau:
WO

Functieomschrijving

Optical nanoscopy is a super-resolution microscopy technique to study subcellular structures and function via specifically targeted fluorescent labels in molecular biology. Localisation microscopy in particular offers a much better resolution (~10-50 nm) than conventional diffraction limited microscopy (~250 nm). This project aims at shifting the resolution obtainable in an optical light microscope even further towards 1 nm.

The researcher will work in a team of experimentalists and theorists who share the common goal to imaging at the nanometer scale. We aim to develop novel data-driven super-resolution reconstruction schemes by employing prior knowledge. The main objective is to reconstruct one complete high resolution image from many incomplete data from chemically identical structures. With this we can estimate the underlying structures.To this end we want to detect potential symmetry of the data and utilize this in the reconstruction pipeline.This will allow to reconstruct an image which much sharper detail than present in each single image alone.

Department
Research in the department of Imaging Physics is aimed at developing novel instrumentation and methodology in imaging science and sensing technology. Our research products extend existing boundaries in terms of spatial resolution, temporal resolution and information/data throughput. We are pioneers in developing advanced concepts of computational imaging, a marriage between cleverly designed imaging systems and sophisticated post-processing. In everything we do, there is a core of cutting edge physics and engineering of high-tech instruments, of the use of the most advanced computing techniques, and of a very close link to real-life applications. Our work has clear societal impact in the areas of life sciences, healthcare, and industry.

The PhD student will work under the guidance of Bernd Rieger and Sjoerd Stallinga who are leading a prominent international research activity in the field of optical nanoscopy. They focus especially on computational microscopy that is the intersection between the fundamentals and engineering of optical imaging systems and image processing algorithms.

Functie-eisen

The candidate must hold a MSc. degree in Physics or Electrical Engineering with a strong background in modeling or simulation. Excellent analytical skills are essential, familiarity with group theory is expected. Experience with numerical simulations and good programming skills are expected. Experience in the fields of image processing, light microscopy or optics is beneficial.

Conditions

TU Delft offers PhD-candidates a 4-year contract, with an official go/no go progress assessment after one year. Salary and benefits are in accordance with the Collective Labour Agreement for Dutch Universities, increasing from € 2395 per month in the first year to € 3061 in the fourth year. As a PhD candidate you will be enrolled in the TU Delft Graduate School. The TU Delft Graduate School provides an inspiring research environment with an excellent team of supervisors, academic staff and a mentor. The Doctoral Education Programme is aimed at developing your transferable, discipline-related and research skills.

The TU Delft offers a customisable compensation package, discounts on health insurance and sport memberships, and a monthly work costs contribution. Flexible work schedules can be arranged. For international applicants we offer the Coming to Delft Service and Partner Career Advice to assist you with your relocation.

Additional information

For information about this vacancy, you can contact Prof.dr. Bernd Rieger, email: b.rieger@tudelft.nl, tel: +31 15 278 8574.