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PhD Position Interactive Optoelectronic Platform for Advanced Investigation of Fibrillation in Real-size Human Atrial Culture Models

An interactive optoelectronic platform to master heart rhythm disorders

ongeveer een jaar geleden


Mekelweg, Delft, Zuid-Holland
Tijdelijk contract / Tijdelijke opdracht
Uren per week:
38 - 40 uur
€ 2395 - € 3061 per maand


Are you looking for an exciting, cutting-edge and truly multidisciplinary project for your PhD training? The Department of Microelectronics (Technical University Delft) and The Laboratory of Experimental Cardiology (Department of Cardiology) have a joint PhD position available for a project combining state-of-the-art LED technology with gene therapy, artificial intelligence and human tissue models to better understand and treat heart rhythm disorders. Are you the candidate that will join our team of engineers, biologists, physicists and physicians to obtain a PhD degree as crucial stepping stone in realizing your dreams? Then join our project and team.

Heart rhythm disorders are initiated and continued by abnormalities in cardiac electrical activity. As the current approaches to study and treat these disorders are suboptimal, this project aims to break new ground by equipping human tissue culture models of heart rhythm disorders with multi-LED arrays to gain superb control over the electrical activity in these models by spatiotemporally controlled illumination, thereby enabling an advanced approach for investigation and treatment. Such optical modulation will be realized through optogenetics, i.e. by the activation of light-sensitive ion channels expressed in these models. This research requires the creation and application of an interactive optoelectronic platform, which is at the core of this PhD training project.

We are looking for a clearly motivated, very determined and creative PhD candidate with a strong interest in electrical engineering, biomedical research, embedded systems and artificial intelligence, but also, including tissue culture modeling of human disease. Experience in any of these fields would be considered an advantage, but the sheer will to make progress by digging into these subjects is equally appreciated. You should combine a winner’s mentality with a great team spirit and strong communication skills as you will collaborate closely with your team members on frontier research. Given the multidisciplinary nature of this project you should be eager to work in both departments, i.e. the Laboratory of Experimental Cardiology in Leiden and the Department of Microelectronics in Delft.


  • You combine a winner’s mentality with a great team spirit and strong communication skills.
  • You hold a recent Master’s degree relevant to this project, for example, but not exclusively, Biomedical Engineering or Sciences, Electrical Engineering, Embedded Systems, or Life Science & Technology.
  • You have an outspoken interest in engineering, system integration, and artificial intelligence, but also biomedical research, including tissue culture modeling of human disease.
  • You are looking for position in a multidisciplinary team to collaborate and you are willing to work at different locations (Leiden and Delft).

In addition to a PhD program and the Graduate School, both Universities (TUD and LUMC) offer opportunities to maintain and develop your knowledge and skills. We offer internal courses and in-service training to help you with your personal development. We also offer services for mobility and career advice.


TU Delft offers a customisable compensation package, a discount for health insurance and sport memberships, and a monthly work costs contribution. Flexible work schedules can be arranged. An International Children’s Centre offers childcare and an international primary school. Dual Career Services offers support to accompanying partners. Salary and benefits are in accordance with the Collective Labour Agreement for Dutch Universities.

As a PhD candidate you will be enrolled in the TU Delft Graduate School. TU Delft Graduate School provides an inspiring research environment; an excellent team of supervisors, academic staff and a mentor; and a Doctoral Education Programme aimed at developing your transferable, discipline-related and research skills. Please visit www.tudelft.nl/phd for more information.

Additional information

For information about this vacancy, you can contact:

Prof. Dr. Guo Qi Zhang, Electronic Components Technology and Materials, +31 15 27 89495, g.q.zhang@tudelft.nl
Dr. Daniël Pijnappels, Head of the Laboratory of Experimental Cardiology, 0715262020, d.a.pijnappels@lumc.nl