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Post-doc position in Live Cell Imaging of DNA Replication and Repair

In this project, you will take on the exciting challenge of understanding DNA replication and repair in bacteria by imaging individual proteins in live cells. …

4 maanden geleden


Van der Maasweg, Delft, Zuid-Holland
Tijdelijk contract / Tijdelijke opdracht
Uren per week:
38 - 38 uur
€ 2984 - € 4084 per maand


In this project, you will take on the exciting challenge of understanding DNA replication and repair in bacteria by imaging individual proteins in live cells. As an independent and motivated post-doctoral researcher, your foremost responsibility will be towards knowledge creation of processes central to DNA replication broadly and replication fork stalling particularly. In doing so, you will be expected to master our state-of-the-art single molecule fluorescence imaging systems capable of probing individual labelled proteins in live bacterial cells under a variety of different conditions. Your critical thinking will also be encouraged towards bringing in new technical expertise if required for the overall research progress. You will be involved in associated genetic engineering where necessary and will analyse the imaged datasets using advanced image processing and biophysical modelling.


We are looking to hire an outstanding experimentalist post-doctoral researcher who would like to build an exciting career with us in interdisciplinary biophysics focused on understanding genome replication using live cell imaging methods. Understanding DNA replication, including aspects such as replication fork stalling and recovery, will entail long-term foresight and short-term planning, quantitative analysis of microscopy data, deep contextual understanding of literature, an ability to employ different and ever-advancing technologies to one’s research question, and the personality balance of exhibiting critical thinking while also being a team player. A strong background in cellular biology or biophysics is a necessity. A good command of spoken and written English is a must.


TU Delft offers a customisable compensation package, a discount for health insurance and sport memberships, and a monthly work costs contribution. Flexible work schedules can be arranged. An International Children’s Centre offers childcare and an international primary school. Dual Career Services offers support to accompanying partners. Salary and benefits are in accordance with the Collective Labour Agreement for Dutch Universities.

For more information about this position, or to submit an application, please contact Prof. Dr. Nynke Dekker, phone: +31 (0)15-2783219, e-mail: n.h.dekker@tudelft.nl. Applications should include a letter of application, a detailed CV, and the names and contact information of three references. The deadline for applications is 30 April 2018. When applying for this position, please refer to vacancy number TNWBN18-019.

Additional information

Prof. Dr. N.H. Dekker
Phone: +31 (0)15 27 83219
E-mail: n.h.dekker@tudelft.nl