Postdoc - Patterning, engineering and characterizing model biofilms

Bacteria living in biofilms can have wide-ranging impacts on society, ranging from threatening human health to purifying drinking water. In order to develop …

26 dagen geleden

Arbeidsvoorwaarden

Standplaats:
Van der Maasweg, Delft, Zuid-Holland
Dienstverband:
Tijdelijk contract / Tijdelijke opdracht
Uren per week:
38 - 38 uur
Salarisindicatie:
€ 2588 - € 4084 per maand
Opleidingsniveau:
Postdoctoraal

Functieomschrijving

Bacteria living in biofilms can have wide-ranging impacts on society, ranging from threatening human health to purifying drinking water. In order to develop new anti-biofilm treatments and to efficiently deploy beneficial biofilms, a reproducible, engineerable biofilm model system is urgently needed. The postdoc will use our home-built 3D bacteria printer in combination with engineered bacteria to create model biofilms. The printed biofilm bacteria will be assessed to study the spatial specialization of metabolism, the three-dimensional pattern of extracellular matrix components, and the ability to resist anti-bacterial treatments. Mechanical characterization of our biofilms through microrheology optical tweezers measurements will determine their physical stability and viscoelastic behavior. We seek to replicate the robustness of natural biofilms, but with control over biological/mechanical properties. These model biofilms will be crucial for future development of anti-biofilm strategies and therapeutics, as well as for the production of beneficial biofilms for use in variable, challenging environments. With the support of technicians and experts in the research team, the postdoc will implement and characterize these model biofilms.   

Functie-eisen

Qualified candidates have a Ph.D. in either biophysics, biochemistry, chemistry, or a related field. They have a strong interest in multidisciplinary research that combines biology with material science. Finally, successful candidates are motivated by a deep scientific curiosity, have good experimental and quantitative skills and possess a drive to learn new methods and concepts.

Conditions

TU Delft offers a customisable compensation package, a discount for health insurance and sport memberships, and a monthly work costs contribution. Flexible work schedules can be arranged. An International Children’s Centre offers childcare and an international primary school. Dual Career Services offers support to accompanying partners. Salary and benefits are in accordance with the Collective Labour Agreement for Dutch Universities.

For more information about this vacancy you can contact Marie-Eve Aubin-Tam, e-mail: m.e.aubin-tam@tudelft.nl. To apply for this position, please send a CV, a letter of interest and names of references to m.e.aubin-tam@tudelft.nl. Please refer to vacancy number TNWBN18-065 in your application.  

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