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The Eindhoven University of Technology (TU/e) has the following vacancy:
PhD candidate in Mechanical Optimization of Osteochondral Implants
TU/e is a University of Technology with a focus on Health, Energy and Mobility. Within the Health area, several departments cooperate on topics such as Chemical Biology, Regenerative Medicine, Computational Biology, and Biosensing, with close links to healthcare and industry. TU/e is an open and inclusive university with short communication lines. The people are curious, collaborative, and strive for excellence. TU/e enables its academic staff to develop research and education at an internationally renowned level. Our lively campus community facilitates connections between staff and students, in an open, friendly, vibrant atmosphere that welcomes and inspires.
The Department of Biomedical Engineering offers a research driven BME Bachelor program and Masters in Biomedical Engineering and Medical Engineering in its Graduate Program. Its research areas range from Molecular Bioengineering and Imaging, Biomechanics and Tissue Engineering to Biomedical Imaging and Modelling. The department has more than 800 students and up to 200 tenured and non-tenured employees.
About the Orthopaedic Biomechanics group:
This group combines the disciplines of engineering and biology to increase our knowledge of the adaptive, developmental and physiological nature of musculoskeletal tissues. This knowledge is then applied to explore and develop regenerative treatment strategies, currently applied to bone, articular cartilage, intervertebral disc and tendons/ligaments. The group consists of multi-disciplinary scientists and engineers at all levels employing numerical and experimental as well as engineering, imaging, biological and chemical techniques.
About RegMedXB and InSciTe:
This vacancy is posted as part of RegMedXB, which stands for 'Regenerative Medicine Crossing Borders'. RegMedXB is a virtual institute composed of universities, health foundations, governments and private companies in the Netherlands and Belgium. The partners work together to tackle some of the greatest challenges in regenerative medicine, while building a community of researchers and companies to realize health and economic benefits. For more information, please visit www.regmedxb.com.
This position is also part of the Chemelot Institute for Science & Technology (InSciTe), a public-private institute for developing smart healing biomedical materials for high quality, affordable healthcare. With its physical nucleus at Brightlands Chemelot Campus, it enables entrepreneurship, expertise, experimentation and education in an open innovation network. In this project, the founding partners, TU/e and DSM, will work together with other RegMedXB partners to achieve their phase-1 aim of bringing a functional regenerative osteochondral implant to first-in-man trials.
We aim to develop a functional regenerative osteochondral implant using a multi-disciplinary approach with various academic centres and industries. One part of the development is to assemble the construct using hydrogels developed at Utrecht University and a fibrous developed in Aachen. This includes developing ways to assemble the hydrogel, cells and scaffolds into a construct, as well as the mechanical characterization thereof. Subsequently, directions for optimization of the mechanical properties will be identified, such that the material ultimately matches the properties of the bone and cartilage it will replace. As these suggestions for optimization involves other parts of the project, there will be close interaction with the entire team.
We are accepting applications from enthusiastic candidates who are interested in a dynamic, stimulating and ambitious environment to perform their work. The candidate must have a Master's degree in biomedical engineering, mechanical engineering, physics or equivalent.
Candidates are expected to have good (bio)mechanical insight, experience with basic mechanical testing techniques, and interested in manufacturing and developing a product and establishing dedicated testing environments. The candidate will be able to effectively communicate scientific ideas, foster collaboration and have a capability for independent thinking. Moreover, the candidate should be able to work independently within a dynamic team and be skilled in written and spoken English.