We are searching for a young scientist who is interested to combine advance optical microscopy and drug delivery nanoparticles. The function is part of the ERC project NANOSTORM. You will learn to use super-resolution microscopy and apply it to study the interactions of nanoparticles with cells and tissues. The objective is to acquire new knowledge about material-cell interactions in order to design novel nanomaterials with potential applications in drug delivery for cancer therapy. The project will benefit of international collaborations with groups active in the field of nanomaterials synthesis and their clinical applications.
About Eindhoven University of Technology (TU/e):
The TU/e is a University of Technology with a focus on Health, Energy and Mobility. Within the Health area, several departments cooperate on topics such as Chemical Biology, Regenerative Medicine, Computational Biology, and Biosensing, with close links to healthcare and industry. The TU/e is an open and inclusive university with short communication lines. The people are curious, collaborative, and strive for excellence. TU/e enables its academic staff to develop research and education at an internationally renowned level. Our lively campus community facilitates connections between staff and students, in an open, friendly, vibrant atmosphere that welcomes and inspires.
About the Department of Biomedical Engineering (BME):
The Department of Biomedical Engineering offers a research driven BME Bachelor program and Masters Biomedical Engineering, Medical Sciences and Technology and Medical Engineering in its Graduate Program. Research areas range from Molecular Bioengineering and Imaging, Biomechanics and Tissue Engineering to Biomedical Imaging and Modeling. The department has more than 800 students and up to 200 tenured and non-tenured employees.
About the Institute for Complex Molecular Systems (ICMS):
The Institute for Complex Molecular Systems is an interdisciplinary institute at Eindhoven University of Technology (TU/e) which brings excellent researchers from different areas together to promote cross-breeding of ideas across disciplines in the departments Biomedical Engineering, Applied Physics, Chemical Engineering and Chemistry, Mathematics and Computer Science, and Mechanical Engineering. The institute aims to create and study biologically relevant functional structures with the ultimate goal of understanding the complexity of life.
The Molecular Biosensing group (MBx, see www.tue.nl/mbx) aims at creating ideas and generating scientific insights in the area of molecular biosensing technologies. This involves the engineering of molecular constructs for sensing applications (using protein, nucleic-acid, and protein-DNA technologies), methods to biofunctionalize nanoparticles, methods to characterize particle behavior in complex environments (e.g. protein corona), the development of novel single-molecule measurement methods, optical microscopies, particle characterization techniques, plasmonic effects, particle actuation principles, signal processing, and simulations. The group develops technologies to detect proteins and study protein function with single-molecule sensitivity in complex macromolecular environments. The research leads to novel methods for molecular biosensing, insights into protein function within complex and crowded environments, and novel routes into point-of-care and patient monitoring applications. Laboratories are shared with the Chemical Biology research group of the Department of Biomedical Engineering (www.tue.nl/cb) and the Institute for Complex Molecular Systems (www.tue.nl/icms).
We are looking for enthusiastic candidates who are in an MSc program or who already have an MSc degree, preferably in Chemistry, Physics, Biomedical Engineering, or Nanotechnology. An interest in Biophysics is required. Experience with mammalian cell culture and biomaterials is required. Additional experience with advanced fluorescence microscopy would be an asset.