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  3. PhD on the Design and Development of Microfluidic Brain-on-Chip AI Computers

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PhD on the Design and Development of Microfluidic Brain-on-Chip AI Computers

The Eindhoven Artificial Intelligence Systems Institute (EAISI) is funding 2 PhD positions for the highly innovative BayesBrain project, in collaboration with …

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de Rondom, Eindhoven, Noord-Brabant
Tijdelijk contract / Tijdelijke opdracht
Uren per week:
38 uur


The Eindhoven Artificial Intelligence Systems Institute (EAISI) is funding 2 PhD positions for the highly innovative BayesBrain project, in collaboration with the departments of

  • Mechanical Engineering,
  • Biomedical Engineering,
  • Electrical Engineering, and
  • Mathematics and Computer Science.

The challenging goal of the project is to design a hybrid neural/in-silico AI computer which leverages the computation of neural cultures hosted on a microfluidic Brain-on-Chip device to solve real-world AI problems. The hybrid AI computer will consist of an in-silico Bayesian control agent and a Brain-on-Chip device, which shall communicate via the common principle of Free Energy Minimization (FEM).

The announced PhD position focuses on the hard-ware development of microfluidic Brain-on-Chip devices and interfaces to in-silico control agents for the purpose of building a hybrid AI computer. For this position, a critical reflection on biomaterials, electrically embedded microfluidic platforms, integrated multi electrode arrays, and fast and high-quality data acquisition systems is required. The successful candidate will design innovative ways to create microfluidic platforms and will have a central role in building the hardware of the hybrid AI system. Furthermore, the techniques developed will be usable for material and toxicity screening, drug development and individualized care and cure. The successful candidate will be hosted at the Department of Mechanical Engineering and co-supervised by Department of Biomedical Engineering.

Paired with the announced position is a second PhD position hosted at the Electrical Engineering department and co-supervised by the Department of Mathematics and Computer Science. The second PhD candidate will focus on the development of in-silico Bayesian control agents via probabilistic programming. The two PhD students will collaborate closely to achieve the final goal of developing a hybrid neural/in-silico AI computer. In particular, the two PhD students will work together on the development of interfaces between the in-silico Bayesian control agent and the Brain-on-Chip device.

The preferred starting date of this position is October 2021.


  • A master's degree (or an equivalent university degree) in Bioengineering, Biotechnology, Materials Engineering, Mechanical Engineering, Microfabrication, with excellent grades
  • Prior experience with microscopy techniques and cell cultures
  • A research-oriented demeanour
  • Ability and aspiration to work in a multi-disciplinary team, combining material science, neuroscience, and probabilistic machine learning
  • Excellent command of written and spoken English

Prior experience with thin layer deposition and metrology techniques is a plus.


  • A meaningful job in a dynamic and ambitious university with the possibility to present your work at international conferences.
  • A full-time employment for four years, with an intermediate evaluation (go/no-go) after nine months.
  • To develop your teaching skills, you will spend 10% of your employment on teaching tasks.
  • To support you during your PhD and to prepare you for the rest of your career, you will make a Training and Supervision plan and you will have free access to a personal development program for PhD students (PROOF program).
  • A gross monthly salary and benefits (such as a pension scheme, pregnancy and maternity leave, partially paid parental leave) in accordance with the Collective Labor Agreement for Dutch Universities.
  • Additionally, an annual holiday allowance of 8% of the yearly salary, plus a year-end allowance of 8.3% of the annual salary.
  • Should you come from abroad and comply with certain conditions, you can make use of the so-called '30% facility', which permits you not to pay tax on 30% of your salary.
  • A broad package of fringe benefits, including an excellent technical infrastructure, moving expenses, and savings schemes.
  • Family-friendly initiatives are in place, such as an international spouse program, and excellent on-campus children day care and sports facilities.

Additional information

Do you recognize yourself in this profile and would you like to know more? Please contact
dr. Regina Luttge, r.luttge[at]tue.nl or +31 40 247 5235 or dr. Burcu Gumuscu Sefunc, b.gumuscu[at]tue.nl or +31 40 247 8373.

For information about terms of employment, click here or contact HRServices.gemini[at]tue.nl.

Please visit www.tue.nl/jobs to find out more about working at TU/e!


We invite you to submit a complete application by using the 'apply now'-button on this page.
The application should include a:
  • a cover letter explaining your motivation and suitability for the position
  • a detailed curriculum vitae
  • a written scientific report in English (MSc thesis, traineeship report or scientific paper)
  • copies of diplomas with course grades (transcripts)

We look forward to your application and will screen it as soon as we have received it. Screening will continue until the position has been filled.

We do not respond to applications that are sent to us in a different way.

Please keep in mind you can upload only 5 documents up to 2 MB each. If necessary, please combine files.