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  3. Postdoctoral fellow - Cardiology (4 years)

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Postdoctoral fellow - Cardiology (4 years)

Heart failure is a major health care problem. It is more and more recognized that co-morbidities such as renal disease and obesity are driving heart failure …

5 maanden geleden

Arbeidsvoorwaarden

Standplaats:
Hanzeplein, Groningen, Groningen
Dienstverband:
Tijdelijk contract / Tijdelijke opdracht
Opleidingsniveau:
WO

Functieomschrijving

Heart failure is a major health care problem. It is more and more recognized that co-morbidities such as renal disease and obesity are driving heart failure and its poor prognosis. A substantial proportion of heart failure patients develop cancer and may die from it, an observation that until now has not received much attention.

The group of Prof. de Boer has a strong interest in the heart failure-oncology connection. By combining experimental and clinical experiments and studies, we have shown that the failing heart may promote tumor growth, and that subjects with (subclinical) heart disease are at risk for cancer development (Circulation 2018).

We will further study this intriguing interaction. Prof. de Boer obtained an ERC consolidator grant (SECRETE-HF), allowing to assemble a team to dive deep into this important phenomenon.

The postdoctoral will be a cornerstone in this new team, and, together with the PI, will shape the project. The successful fellow must have solid background in molecular cardiology or oncology, preferable have knowledge of heart disease or failure, with expertise in cell and animal models. She/he will study several models of heart failure and the consequences on cancer formation, using a wide array of methodology, including proteomic and metabolomic strategies. We will explore several novel exciting leads that recently came up in screens we performed. The postdoctoral fellow will have opportunity to devote 100% of his/her time to the research projects, and we of course welcome exciting ideas that the candidate may come up with.

What are the opportunities for you
- You are part of a great team, with strong interaction between experimental, genetic, epidemiological and clinical research groups, all on one floor.
- The PI is present, interacts with you, and has weekly meetings.
- We are well-funded and you will have access to all resources needed for your project.
- There are 3 PhD students working on this topic, which will be working in a team with you, in part under your supervision.
- We are leading in this novel field, and have strong connections with the cardio-oncology community in Europe and the USA.

Functie-eisen

- a PhD degree in a cardiology/oncology field
- experience with experimental animals
- affinity with cell culture techniques and biochemistry
- good English writing and communication skills
- organizational talents
- 2 references

The UMCG has a preventive Hepatitis B policy. The UMCG can provide you with the vaccination, should it be required for your position.

In case of specific professions a ‘Certificate of Good Conduct’ is required.

Conditions

We offer a full-time appointment for one year, with the possibility of extension for a maximum of four years.
Your salary will be a maximum of €4,361 gross per month (scale 10), depending on your qualifications and relevant experience, based on a full-time appointment.
In addition, the UMCG will offer you 8% holiday pay, an 8.3% end-of-year bonus.
The conditions of employment comply with the Collective Labour Agreement for Medical Centres (CAO-UMC). English: http://www.nfu.nl/english/about-the-nfu/

More information
For more information about this vacancy you may contact:
Prof. Rudolf de Boer, cardiologist, r.a.de.boer@umcg.nl (please do not use for applications).

Description of the Institute and the lab

Applying for a job
Please use the the digital application form at the bottom of this page - only these will be processed.
You can apply until 10 June 2019.
Please state in your CV the names and contact information of at least two references and add a short biosketch.

Within half an hour after sending the digital application form you will receive an email- confirmation with further information.