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  3. PhD candidate Supramolecular biomaterials for 3D cell culture of induced pluripotent stem cells and their derivatives

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PhD candidate Supramolecular biomaterials for 3D cell culture of induced pluripotent stem cells and their derivatives

Supramolecular materials are attractive for use in the biomedical area because of their capacity to be modular, mechanically tunable, responsive and …

7 maanden geleden

Arbeidsvoorwaarden

Standplaats:
Einsteinweg, Leiden, Zuid-Holland
Dienstverband:
Tijdelijk contract / Tijdelijke opdracht
Uren per week:
38 uur
Salarisindicatie:
€ 2266 - € 2897 per maand
Opleidingsniveau:
WO

Functieomschrijving

Supramolecular materials are attractive for use in the biomedical area because of their capacity to be modular, mechanically tunable, responsive and biomimetic. This project explores their application as scaffolds for 3D cell culture in the differentiation of induced pluripotent stem cell (iPS) to cardiomyocytes. Taking inspiration from the complexity of the natural extracellular matrix (ECM) in their design, these materials will be used to unravel the biophysical-biochemical coupling of cues in the cardiac stem cell niche during development. The aim is to prepare mature cellular equivalents of cardiomyocytes for future applications in disease modeling by a materials approach.

Functie-eisen

  • Master’s degree in (Bio)Chemistry;
  • Good to excellent proficiency in English;
  • Ability to work independently in a multidisciplinary environment;
  • Required experience: organic synthesis of small molecules and their characterization;
  • Experience with tissue culture and/or characterization of soft materials is preferred;
  • The PhD research needs preferable to start before March 2019.

Conditions

We offer a full-time 1 year term position for initially one year. After a positive evaluation of the progress of the thesis, personal capabilities and compatibility the appointment will be extended by a further three years. Salary range from €2,266 to €2,897 gross per month (pay scale P in accordance with the Collective Labour Agreement for Dutch Universities).

Leiden University offers an attractive benefits package with additional holiday (8%) and end-of-year bonuses (8.3%), training and career development and sabbatical leave. Our individual choices model gives you some freedom to assemble your own set of terms and conditions. Candidates from outside The Netherlands may be eligible for a substantial tax break.

All our PhD students are embedded in the Leiden University Graduate School of Science. Our graduate school offers several PhD training courses at three levels: professional courses, skills training and personal effectiveness. In addition, advanced courses to deepen scientific knowledge are offered by the research school.

Diversity
Leiden University is strongly committed to diversity within its community and especially welcomes applications from members of underrepresented groups.

Additional information

Enquiries can be made to Roxanne Kieltyka, email r.e.kieltyka@chem.leidenuniv.nl. If you have any questions about the procedure, please contact Michelle van der Haar, email m.haar@chem.leidenuniv.nl.

Applications
To apply for this vacancy, please send no later than 16 February 2019 an email to the secretary of the Supramolecular and Biomaterials Chemistry group, Michelle van der Haar at m.haar@chem.leidenuniv.nl.
Please ensure that you join to your application the vacancy number and the following additional documents:

  • A letter of motivation
  • An updated CV
  • The letters of recommendation by 1 or 2 former supervisors
  • The transcripts of your MSc studies