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  3. Research Assistant on the subject of multiscale modelling of the gut microbiota in infants

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Research Assistant on the subject of multiscale modelling of the gut microbiota in infants

The opening is for a research position, within the field of mathematical or theoretical biology, applied mathematics or computational science The central …

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Arbeidsvoorwaarden

Standplaats:
Sylviusweg, Leiden, Zuid-Holland
Dienstverband:
Tijdelijk contract / Tijdelijke opdracht
Uren per week:
38 uur
Salarisindicatie:
€ 2579 - € 3445 per maand
Opleidingsniveau:
WO

Functieomschrijving

The opening is for a research position, within the field of mathematical or theoretical biology, applied mathematics or computational science

The central hypothesis of the project is that the intestinal microbiota of the infant contributes to the physiological performance. The microbial composition and metabolic product blend, due to digestion, are linked with each other. The microbial products can be produced with various physiological effects. The aim of this project is to identify control strategies for steering the microbial composition and the production of selected metabolic products by the gut microbiota.
The objective of the project is to further develop our existing, spatial, multiscale simulation platform of the gut microbiota (Van Hoek and Merks, BMC Systems Biology 2017) towards a platform that can be a hypothesis generator for how nutritional composition and structure of dairy products is linked to digestive performance in the infants. The model includes detailed metabolism of bacterial populations based on flux-balance analysis, partial-differential equations to model the exchange of nutrients, and agent-based models of bacterial population dynamics.

Functie-eisen

  • Master’s degree in applied mathematics, computational physics, theoretical biology, computer science or a related discipline;
  • Good to excellent written and oral proficiency in English;
  • Ability to work independently in a multidisciplinary environment;
  • Ability to communicate with scientists in biology and mathematics;
  • Experience in mathematical modeling (e.g., agent-based simulations, PDEs, FBA);
  • Excellent programming skills in C++.

Conditions

We offer a temporary position for one year. The position may be prolonged to a period of maximum four years, in which case the candidate is expected to work towards an academic promotion. The one-year position will be financed by, and will be carried out in part at a large international food company. After a positive evaluation of the interest of the project for the dairy company, personal capabilities and compatibility, it is possible that the appointment can be turned into a PhD appointment in which case it will extended by a further three years. Salary range from €2,579 to €3,445 gross per month (pay scale 8 in accordance with the Collective Labour Agreement for Dutch Universities).

Leiden University offers an attractive benefits package with additional holiday (8%) and end-of-year bonuses (8.3 %), training and career development and sabbatical leave. Our individual choices model gives you some freedom to assemble your own set of terms and conditions. For international spouses we have set up a dual career programme. Candidates from outside the Netherlands may be eligible for a substantial tax break. More at https://www.universiteitleiden.nl/en/working-at/job-application-procedure-and-employment-conditions.

Diversity
Leiden University is strongly committed to diversity within its community and especially welcomes applications from members of underrepresented groups.

Additional information

For more information please contact Professor Roeland Merks, email merksrmh@math.leidenuniv.nl, telephone +31 71 527 7106.

Applications
Applications including the vacancy number can be sent no later than 8 March 2019 to sylvius@biology.leidenuniv.nl.

Enquiries from agencies are not appreciated.