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  3. PhD Position: Predicting Efficacy of neuromodulation in epilepsy

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PhD Position: Predicting Efficacy of neuromodulation in epilepsy

Within the Clinical Neurophysiology group of the Institute of Technical Medicine we have availablea PhD position for a project entitled: Predicting Efficacy …

2 maanden geleden

Arbeidsvoorwaarden

Standplaats:
Drienerlolaan, Enschede, Overijssel
Dienstverband:
Tijdelijk contract / Tijdelijke opdracht
Uren per week:
40 - 40 uur
Salarisindicatie:
€ 2434 - € 3111 per maand
Opleidingsniveau:
WO

Functieomschrijving

Within the Clinical Neurophysiology group of the Institute of Technical Medicine we have available

a PhD position for a project entitled: Predicting Efficacy of Neuromodulation in Epilepsy (PREDYct)

In patients with medically refractory epilepsy vagus nerve stimulation and deep brain stimulation are possible treatment options. While effective in several patients, about 30-50% of patients do not respond favorably to this treatment.

This project aims to identify novel biomarkers to predict the success of vagus nerve stimulation (VNS) using ultra-long (up to more than a year) EEG measurements with a subcutaneous electrode (© UNEEG). This is complemented with (functional) MRI and high-density EEG recordings. Patients who are candidates for VNS will be implanted with the UNEEG device 2 months before implantation of the VNS. Treatment effects will be evaluated with the UNEEG electrode, complemented with diaries and questionnaires regarding epilepsy related symptoms. At present, four patients have been implanted with the UNEEG electrode.

This project is a collaboration between the CNPH group of the University of Twente, the Neurocenter group (neurosurgery, neurology and clinical neurophysiology) of the Medisch Spectrum Twente and the epilepsy center SEIN in Zwolle.

This project is funded by the Dutch epilepsy foundation, EpilepsyNL.

Functie-eisen

We are looking for a highly motivated researcher with an MSc degree in Technical Medicine or Biomedical Engineering. A very strong interest in clinical research, epilepsy, biomedical signal analysis and machine learning is essential.

Candidates need to have good social skills and must like to work in an interdisciplinary and internationally oriented environment. An interview and presentation will be part of the selection procedure.

Conditions

We offer a scientific education on a multidisciplinary subject. The assignment is for four years, with a go/no go assessment at the end of the first year.

The university offers a dynamic ecosystem with enthusiastic colleagues in which internationalization is an important part of the strategic agenda.
  • The gross monthly salary starts with € 2.434,- in the first year and increases to € 3.111,- in the fourth year of your employment
  • A holiday allowance of 8% of the gross annual salary and a year-end bonus of 8.3%
  • A solid pension scheme
  • Minimum of 29 holidays in case of full-time employment
  • Professional and personal development programs

Additional information

Applications are welcome before November 1st, 2021 and should include a specific motivation letter reflecting on the goal and challenges of the advertised project in relation to the interests and skills of the candidate as well as a detailed CV (CV, copies of Master and Bachelor degree certificates including supplements as well as copies of other relevant documents (e.g. publications).

For more information, please contact: Prof. dr. ir. M.J.A.M. van Putten, neurologist (m.j.a.m.vanputten@utwente.nl)