Postdoctoral researcher in computational biology: Molecular Networks of Alternative life
(Astro-)physicists, chemists and biologists from four research institutes (API, HIMS, IBED and SILS) of the University of Amsterdam have set up a …
- Science Park, Amsterdam, Noord-Holland
- Vast contract
- Uren per week:
- 38 - 38 uur
- € 2790 - € 4402 per maand
(Astro-)physicists, chemists and biologists from four research institutes (API, HIMS, IBED and SILS) of the University of Amsterdam have set up a collaborative research and training program on the origins and fundamental aspects of life, including the possibilities for life elsewhere in the universe. This is part of a larger national research activity on ‘Origins and Evolution of Life – on Earth and in the Universe’, one of the routes that were defined in the National Research Agenda (Nationale Wetenschapsagenda NWA). The faculty of science will start 4 projects, and this position is part of the BioNAL project.
Life anywhere might be very much like life-as-we-know-it (which is pretty homogeneous), but need not be. It may well be highly different. The same goes for new life forms, which we want to investigate bottom-up and top-down using synthetic methods. Life will need to have a minimal complexity in order to fulfill a number of requirements that are common to all autonomous life forms (CCEMM: containment, catalysis, Gibbs free energy harvest and dissipation, memory and molecular mobility). This in turn requires the networking of molecules. In a computational biology top-down approach, we will build networks of alternative components fulfilling requirements for autonomous life. In an experimental chemistry bottom-up approach, we will investigate sets of possible alternative building blocks forming alternative components. This is a highly innovative project, as it combines minimal complexity and network models, synthetic chemistry and synthetic biology.
The computational biology part will consist of the design of (metabolic) networks with new components, and the creation of methods to study the minimal properties of life, and suggest compounds and networks that could fulfill those properties
What are you going to do?
In the research project entitled Biomarker Networks of Alternative Life (BioNAL), the successful candidate will:
- collaborate with another postdoc at the chemistry department and staff members from the four participating institutes;
- develop computational models for metabolic networks of alternative life;
- join the national and local Origins Center networks and interact with other projects within these networks;
- report your results in peer-reviewed journals and at international conferences.
What do we require?
- A PhD in Computational Biology or a closely related field;
- interest to collaborate in an interdisciplinary team, mainly with the chemistry department;
- good communication skills in oral and written English;
- experience with modelling of metabolic networks will be advantageous;
- an inclination for outreach would be a plus.
A temporary contract for 38 hours per week, preferably starting at 1 January 2021 for the duration of 24 months (or equivalent).
The salary, depending on relevant work experience before the beginning of the employment contract, will be €2,790 to €4,402 (scale 10) gross per month, based on a full-time contract of 38 hours a week. This is exclusive 8 % holiday allowance and 8,3% end-of-year bonus. A favourable tax agreement, the ‘30% ruling’, may apply to non-Dutch applicants. The Collective Labour Agreement of Dutch Universities is applicable.
Are you curious about our extensive package of secondary employment benefits like our excellent opportunities for study and development? Take a look here.
Do you have questions about this vacancy? Or do you want to know more about our organisation? Please contact:
dr Meike Wortel, assistant professor
T:+ 31 (0)20 525 7025