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The Dutch urban drainage sector invests approximately 1.5 billion euros annually to provide crucial sewerage services, such as safe drainage and the …
In collaboration with Agroscope at the Federal Office of Agriculture in Switzerland, we are offering a PhD position in the field of biomarkers, metabolomics …
In collaboration with Agroscope at the Federal Office of Agriculture in Switzerland, we are offering a PhD position in the field of biomarkers, metabolomics and human nutrition.
The PhD thesis is a will be centered on the Cardioferment project which objective is to associate acute markers of intake of fermented foods with cardiometabolic factors in a real-life observational cohort. The project will use existing data from a series of short-term human intervention studies with dairy products (acute and two-week) in which putative biomarkers of fermented dairy foods have been established. The Cardioferment project will validate these data in a prospective cohort nutritional study "Nutrition Questionnaire plus" (NQplus), an ongoing longitudinal study on diet and health in the Netherlands following 2,048 men and women. The NQplus cohort is characterized by multiple dietary assessments as well as anthropometric, cardiometabolic, blood and urine measurements.
The Cardioferment project will encompass: (i) the analysis of the dietary patterns of the NQplus study participants, focusing on consumption of fermented foods/ fermented dairy products, (ii) the association of anthropometric measures and cardiometabolic markers to dietary patterns, and (iii) urine and serum metabolomics on a selected number of participants by GC-MS and LC-MS.
The PhD will use the metabolomics data to confirm biomarkers of food intake before investigating nutritional biomarkers of health, by associating biomarkers of the intake of fermented foods and fermented dairy products with anthropomorphic and cardiometabolic measures of the NQplus cohort. Part of the work will take place in Bern, Switzerland at Agroscope.
For this international collaborative project we are looking for a PhD student who will use metabolomics data to confirm biomarkers of food intake, before investigating nutritional biomarkers of health.
We are looking for enthusiastic and highly motivated candidates with: