1. Vacatures
  2. Universiteit Leiden (LEI)
  3. Postdoctoral fellow, Modeller environmental fate and effects of engineered nanomaterials

Postdoctoral fellow, Modeller environmental fate and effects of engineered nanomaterials

The Faculty of Science and Institute of Environmental Sciences are looking for a Postdoctoral fellow Modeller environmental fate and effects of engineered nanomaterials

15 dagen geleden

Arbeidsvoorwaarden

Standplaats:
Einsteinweg, Leiden, Zuid-Holland
Dienstverband:
Tijdelijk contract / Tijdelijke opdracht
Uren per week:
30 - 38 uur
Opleidingsniveau:
Postdoctoraal

Functieomschrijving

Efficient environmental safety evaluation of engineered nanomaterials (ENM) requires a growing need of predictive models. Development of properly validated models for predicting ENM toxicity constitutes a great opportunity to optimize ENM evaluation, to reduce ethical considerations related to toxicity testing, and to design novel ENMs that are safer-by-design. As partners within the EU-funded project NanoInformaTIX, we want to contribute by developing dose-response models. QSAR-type models will be developed for in vitro and in vivo endpoints, based on a full characterisation of ENMs using both existing descriptors and the 2nd generation descriptors, more specific omics data accounting for mechanistic modelling. Ultimately for in vitro models the challenge is to extrapolate across human models or to ecological species using appropriate allometric scaling. Physiologically based pharmaco-kinetics (PBPK) models will be applied as the basis for describing in vivo exposure-dose-response relationships. Within this project we are able to hire one postdoctoral fellow for 20 months.

Key responsibilities

  • Modeling dose-response models of emerging nanomaterials;
  • Justify read across species theories and model similarity based on ENM properties as well as effect endpoints;
  • Linking human to ecological toxicity mechanisms;
  • Collaborate and represent Leiden University with the modellers of the NanoInformaTIX consortium that consists of European experts of various countries.

Functie-eisen

  • You should have a PhD in a relevant field, and ideally have proven already to be productive in terms of scientific output. Relevant backgrounds include PhD’s in ecotoxicology, risk analysis, theoretical biology, sustainability science, or data science;
  • Extensive modelling skills;
  • You must be proficient in spoken and written English, and have good communication skills. Previous teaching experience will also be valued;
  • Moreover, you work well in a team, and are able to support the coaching and guidance of PhD students.

Conditions

We offer a 20 month term position with the possibility of renewal based on need, funding and performance. The salary range is from €2,707 - €4,274 gross per month (pay scale 10 in accordance with the Collective Labour Agreement for Dutch Universities).

Leiden University offers an attractive benefits package with additional holiday (8%) and end-of-year bonuses (8.3 %), training and career development and sabbatical leave. Our individual choices model gives you some freedom to assemble your own set of terms and conditions. For international spouses we have set up a dual career programme. Candidates from outside the Netherlands may be eligible for a substantial tax break. 

Additional information

Diversity 
Leiden University is strongly committed to diversity within its community and especially welcomes applications from members of underrepresented groups.

Information 
Enquiries can be made to Prof.dr. Martina Vijver and Prof.dr. Willie Peijnenburg.

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