In this project new types of Nanodiscs will be employed to enable applications in vaccine development and screening in drug development. Several well-characterized and medically relevant membrane proteins will be produced and inserted into Nanodiscs. The constructs will be characterized with biophysical techniques and screening tests will be performed. Also, immunogenicity and toxicity of the new constructs will be determined. The postdoctoral researcher will be expected to carry out the biophysical characterization as well as to oversee the entire project, and will be collaborating closely with the technician appointed to this project for the production of the membrane proteins. The project is a collaboration of Leiden University, Batavia Biosciences and ZoBio, all located at the Leiden Bioscience Park. The postdoctoral researcher will be seconded for several months to Batavia Biosciences at their site in Boston, MA. The remainder of the work will be carried out at the Leiden Institute of Chemistry.
- PhD degree in Biophysics, Biochemistry or Molecular Biology;
- Ability to work independently in several research groups;
- Team player with initiative;
- Experience with membrane protein purification and Nanodiscs.
The duration of the project is three years. We offer a position, initially for one year and with the possibility of a renewal for two years based on good performance. Salary range from €2,588 to €4,084 gross per month (pay scale 10 in accordance with the Collective Labour Agreement for Dutch Universities).
Leiden University offers an attractive benefits package with additional holiday (8%) and end-of-year bonuses(8.3 %), training and career development and sabbatical leave. Our individual choices model gives you some freedom to assemble your own set of terms and conditions. Candidates from outside the Netherlands may be eligible for a substantial tax break. More at https://www.universiteitleiden.nl/en/working-at/job-application-procedure-and-employment-conditions.
Leiden University is strongly committed to diversity within its community and especially welcomes applications from members of underrepresented groups.
Enquiries can be made to Professor Marcellus Ubbink, email firstname.lastname@example.org, Telephone +31 71 5274628.
To apply for this vacancy, address your application to Professor Ubbink and send it by email no later than 21 May 2018 to Mrs I. Bekooy at email@example.com. Please ensure that you include the following additional documents quoting the vacancy number:
- A motivation letter explaining your interest and qualifications for this position;
- Names, affiliations and e-mail addresses of three references. Also indicate your relationship to them (thesis supervisor, etc.).