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PhD candidate 4 years Project title: Value of Ultra High field MRI for focal epilepsy (EpiUltra study)

The School for Mental Health and Neuroscience has a vacancy for a PhD student 4 years

Project title: Value of Ultra High field MRI for focal epilepsy (EpiUltra study)

19 dagen geleden

Arbeidsvoorwaarden

Standplaats:
P Debyelaan, Maastricht, Limburg
Dienstverband:
Tijdelijk contract / Tijdelijke opdracht
Uren per week:
36 - 40 uur
Salarisindicatie:
€ 2325 - € 2972 per maand
Opleidingsniveau:
WO

Functieomschrijving

Background

Finding a relevant brain lesion in a patient with chronic epilepsy may improve his/her options for treatment and chances for cure completely. Unfortunately, for many individuals with chronic epilepsy still no lesion becomes visible on the clinical MRI (3-Tesla). With the current study we want to make use of higher field strength MR scanners and advanced analysis methods to investigate whether this improves the detection of (small) brain lesions in patients with focal epilepsy. This will potentially result in better treatment chances and a better seizure outcome after epilepsy surgery.

Setting

This 4-year project is a multidisciplinary collaboration between the Maastricht University Medical Center (MUMC+) and Kempenhaeghe epilepsy center in Heeze (ACE). Scanning will take place at the ultra-high-field MRI center (Scannexus) in Maastricht.  The research requires an intense collaboration between multiple medical disciplines, for instance neurosurgery, neurophysiology and radiology, as well as imaging scientists and medical physicists. For the academic career the PhD trajectory will be conducted /imbedded in the setting of the research school Mental Health & Neuroscience (MHeNs) of the University Maastricht UMC+.

Tasks

  • Literature study on UHF-MRI in epilepsy
  • Study on epilepsy and epilepsy surgery and attending meetings of the multidisciplinary epilepsy surgery working group (Heeze and Maastricht)
  • Data collection including images and medical records
  • Application and development of novel medical image analysis techniques
  • Presentation of findings in a thesis, scientific publications and at (inter)national conferences
  • Teaching and supervision of Master students

Functie-eisen

For this project, advanced image analysis will be used. Therefore, we are looking for a candidate with a MSc, affinity for medical imaging and a background in biomedical or electrical engineering, physics, data science, computational neuroscience, or other related fields. Good programming skills (for instance MATLAB) are important for successful completion of this project, and also some knowledge of and interest in machine learning can be beneficial. In addition, the candidate should have a keen interest in (learning) clinical examination methods on patients, preferably speak the Dutch language, be flexible, open-minded and curious with strong analytical and conceptual skills.

Conditions

The terms of employment of Maastricht University are set out in the Collective Labour Agreement of Dutch Universities (CAO). Furthermore, local UM provisions also apply. For more information look at the website http://www.maastrichtuniversity.nl > Support > UM employees.

Additional information

For further information, please contact dr Olaf Schijns, neurosurgeon (043-3874041; o.schijns@mumc.nl), dr. Jaap Jansen, imaging scientist (043-3874908; jaap.jansen@mumc.nl), or prof.dr.ir. Walter Backes, medical physicist (043-3874911; w.backes@mumc.nl).

Application

Interested candidates should send

  • A letter of motivation
  • A detailed CV
  • Contact info of at least two references