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PhD candidate or Postdoc in Genetic Data Analysis

Project description Recent genome-wide studies have led to unprecedented progress in understanding the genetic architecture of brain-related traits and …

6 maanden geleden

Arbeidsvoorwaarden

Standplaats:
De Boelelaan, Amsterdam, Noord-Holland
Dienstverband:
Tijdelijk contract / Tijdelijke opdracht
Uren per week:
32 - 40 uur
Salarisindicatie:
€ 2222 - € 4757 per maand
Opleidingsniveau:
WO

Functieomschrijving

Project description
Recent genome-wide studies have led to unprecedented progress in understanding the genetic architecture of brain-related traits and disorders, such as schizophrenia, depression, insomnia and intelligence. In this project we aim to advance our understanding of these results in biological context. We will develop and apply novel statistical and bioinformatic tools, and use new, biologically informative resources. Connecting the dots between different lines of evidence is the central theme in this project, aiming to advance insight into neurobiological pathways of neuro-cognitive traits, and generate testable hypotheses for functional follow-up experiments.

Tasks
We are seeking a highly motivated, talented individual. There is one vacant position, which can either be filled by a PhD candidate or by a Postdoc. You will be working with large genetic and genomic datasets, with information on brain related traits (e.g. cognition, schizophrenia, autism, mental retardation, neurodegenerative disorders), as well as reference datasets containing information on e.g. mRNA expression, proteomics or methylation. We are looking for a candidate with good programming skills. an understanding of principles of molecular genetics, and knowledge of e.g. chromatin interactions, gene expression, and epigenetics, and preferably good knowledge of in statistical genetics. Practical experience in the analysis of genomics data (e.g. expression data, GWAS, WGS, WES) is a pré.

Functie-eisen

For the PhD position: Minimum qualifications include an MSc. degree in any of the following fields: bioinformatics, statistics, medical statistics, statistical genetics, computer programming, computational biology or related quantitative/computational field. For the Postdoc position we require a PhD in any of the above fields and demonstrable experience in genetic data analysis.
In addition we require a good ability to write and read English, experience working with large datasets, strong computer programming skills, and experience with the R statistical language and working in a UNIX environment. Wet lab experience is not necessary.

Conditions

The initial appointment will be for a period of 1 year. After satisfactory evaluation of the initial appointment, it will be extended for a total duration of 4 years (PhD) or 3 years (Postdoc). Information about our excellent fringe benefits of employment can be found at www.workingatvu.nl and include for example:
• Remuneration of 8,3% end-of-year bonus and 8% holiday allowance;
• Solid pension scheme (ABP);
• A minimum of 29 holidays in case of full-time employment;

Salary
The salary will be in accordance with university regulations for academic personnel, and ranges from a minimum of € 2222,00 gross per month (salary scale 85) up to a maximum of € 2840,00 gross per month based on a fulltime employment (PhD student) or between € 3111,00 and € 4757,00 (salaryscale 10/11, depending on experience) for a Postdoc.

Additional information

For additional information please contact:
Prof.dr. D. Posthuma
phone +31 (0)20 59 82823