Postdoc Human ex vivo model to study nonalcoholic fatty liver disease (1.0 FTE)

Description

The Groningen Research Institute of Pharmacy (GRIP) in the Faculty of Science and Engineering has a position for a Postdoctoral Fellow in the Pharmaceutical Technology and Biopharmacy group. We offer a challenging, interdisciplinary research project whose aim it is to develop a microfluidic biological model to study nonalcoholic fatty liver disease, termed Non-Alcoholic SteatoHepatitis (NASH). The objectives of the project are to (1) address the induction of steatosis in the liver utilizing an ex vivo precision-cut liver slice model (2) to develop a microfluidic device to study the effect of the effluent of nonalcoholic fatty liver precision-cut liver slices on human effector cells (e.g. fibroblasts and cancer cells) (3) to identify NASH-specific biomarkers.

You will be working in a stimulating interdisciplinary biomedical team including cell biologists, analytical chemists, and medical clinicians. You will be involved in the supervision of PhD students. There will be close collaboration with the Pharmaceutical Analysis group in GRIP (Prof Sabeth Verpoorte, microfluidics) and with the University of Mainz (Prof Detlef Schuppan, NASH).

Background
www.rug.nl/research/grip/news/news/meer-kennis_-met-minder-dieren_-%28zonmw%29-grant-for-olinga

Requirements

The candidate must have knowledge of, and research experience in, the biomedical sciences and/or cell biology as evidenced by a successful PhD research project with publications/conference presentations. Creative thinking, initiative, management skills and good verbal and written English proficiency are a necessity. Proficiency in the Dutch language would be an asset, as would be experience with culturing of precision-cut tissue slices. You are enthusiastic, ambitious, and a team player.

Conditions

The University of Groningen offers a salary dependent on qualifications and work experience of € 3,111 gross per month up to a maximum of € 4,084 gross per month (salary scale 10 Dutch Universities) for a full-time position excluding a 8% holiday allowance and a 8.3% end of the year bonus. The appointment is for a period of three years (38 hours work week).
Work location is the Pharmaceutical Technology and Biopharmacy group, in GRIP, University of Groningen, in Groningen, The Netherlands.

A personal budget of € 1,000 per year is dedicated for additional training and career activities.

The University of Groningen provides career services for partners of new faculty members moving to Groningen.

The University of Groningen has adopted an active policy to increase the number of female scientists across all disciplines of the University. Therefore, female candidates are especially encouraged to apply.

The successful candidate will first be offered a temporary position of three years.

The preferred starting date is September 2018.

How to apply
You may apply for this position until 14 August 23.59h / before 15 August 2018 Dutch local time by means of the application form (click on "Apply" below on the advertisement on the university website).

The application should include:

- CV
- motivation letter
- copy of the PhD diploma or estimated time of graduation
- contact details of 3 academic references.

Unsolicited marketing is not appreciated.

Additional information

Prof. Peter Olinga
+31 50 3638373,
P.Olinga@rug.nl