PhD in blood flow simulations

Are you ambitious, passionate about science, and eager to solve complex biomedical questions through computational methods? We (the Computational Science …

13 dagen geleden

Arbeidsvoorwaarden

Standplaats:
Science Park, Amsterdam, Noord-Holland
Dienstverband:
Tijdelijk contract / Tijdelijke opdracht
Uren per week:
38 - 38 uur
Salarisindicatie:
€ 2325 - € 2972 per maand
Opleidingsniveau:
WO

Functieomschrijving

Are you ambitious, passionate about science, and eager to solve complex biomedical questions through computational methods? We (the Computational Science Laboratory) are looking for a PhD candidate to join our team of researchers.

What are you going to do?

Your main objective will be to develop, validate, and apply a new computational model to simulate the flow of red blood cells, platelets, and other components under specific disease and medical device related conditions. You will build on the Multiscale Modelling and Simulation Framework and develop your model within HemoCell to realize an efficient, high performance computational method that can provide answers to complex biological questions in the context of human vascular diseases, such as thrombosis, hemostasis. You will cooperate with external experimental groups throughout the process.

You will:

  • develop a new multiscale computational model within HemoCell, adding the molecular level, adding biochemistry, and adding platelet adhesion and aggregation, and apply it in the context of human vascular diseases;
  • complete and defend a PhD thesis within the official appointment duration of four years;
  • collaborate with other researchers within our group and in external groups;
  • regularly present intermediate research results at international conferences and workshops, and publish them in proceedings and journals;
  • assist in relevant teaching activities.

Background information

The Multiscale Modelling and Simulation Framework defines a theoretical approach to multiscale modelling, a simulation framework to develop and run multiscale simulations and a set of tools and middleware to execute and manage multiscale computations on a broad array of computing infrastructure, from the desktop to HPC environments.

HemoCell is our open-source cellular flow modelling toolkit. It is used by several groups around the world in investigations spanning from basic research topics on cellular transport mechanism to more applied topics on endovascular medical devices.

Functie-eisen

  • A Master's degree in computational science, computational biology/physics, physics, applied mathematics, or in a closely related discipline;
  • a strong background in programming (C++ and Python preferred);
  • a strong interest in biology, biophysics or biomedicine related questions;
  • good communication, presentation and writing skills and excellent command of English;
  • pro-active, cooperative attitude and creative out-of-the-box thinking;
  • capability to work in an international multidisciplinary research environment.

Knowledge on the following is not required, but considered as an advantage:

  • computational fluid dynamics;
  • numerical techniques to solve PDEs;
  • lattice Boltzmann method;
  • high performance computing.

Conditions

A temporary contract for 38 hours per week, preferably starting at 1 november 2020 for the duration of 18 months. After a satisfactory evaluation the contract will be extended for 30 months and should lead to a dissertation (PhD thesis). You will get a customized Training and Supervision Plan, that will be evaluated every year.

The salary will be €2,325 to € 2,972 (scale P) gross per month, based on fulltime (38 hours a week), exclusive 8 % holiday allowance and 8.3 end-of-year bonus. A favorable tax agreement, the ‘30% ruling’, may apply to non-Dutch applicants. The Collective Labour Agreement of Dutch Universities is applicable.

Some further things we offer:

  • very friendly, interactive and international working environment;
  • new building located near the city center (20 minutes by bicycle) of one of Europe’s most beautiful and lively cities;
  • access to high-end computing facilities (e.g. cluster with 4,000+ cores).

Are you curious about our extensive package of secondary employment benefits? Then find out more about working at the Faculty of Science.

Additional information

Do you have questions about this vacancy? Or would you like to know more about our organisation? Please contact:

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