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PhD position in Sex- and Gender-Specific Gene Expression

The Department of Biological Psychology Vrije Universiteit Amsterdam, is offering a four-year PhD studentship focused on the topic of gender and sex differences in psychopathology, and sex differences in gene expression in the brain. There ...

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Arbeidsvoorwaarden

Standplaats:
De Boelelaan, Amsterdam, Noord-Holland
Dienstverband:
Tijdelijk contract / Tijdelijke opdracht
Uren per week:
40 uur
Salarisindicatie:
€ 2222 - € 2840 per maand
Opleidingsniveau:
WO

Functieomschrijving

The Department of Biological Psychology Vrije Universiteit Amsterdam, is offering a four-year PhD studentship focused on the topic of gender and sex differences in psychopathology, and sex differences in gene expression in the brain.
There are substantial sex-differences in the prevalence of psychiatric disorders; autism spectrum disorders, substance use and ADHD are more common in males, eating disorders, depression and anxiety are more common in females. For a good understanding of disease etiology, as well as for diagnosis, prevention, and intervention purposes, it is of importance to improve our understanding of the causes of sex-differences.
While genes play an important role in psychiatric disease etiology, there is limited evidence of genetic differences between male and female disease etiology. However, gene expression and epigenetic regulation do differ between sexes, providing a potential mechanism of biological sex differentiation. In this project, the PhD student will use state-of-the-art methodology and large genetic datasets to investigate sex-specific gene expression and epigenetics, and relate these to sex differences in psychiatric traits, with a focus on depression, anxiety, addiction, and schizophrenia. Findings will improve our understanding of sex-differences in psychiatric disorders and can inform sex-specific interventions for psychiatric traits.

Functie-eisen

• A completed MSc degree in the field of Psychology, Methodology, Neuroscience, Computer Science, Genetics;
• Experience working with R or similar programming language;
• Affinity for the topic;
• Proven statistical and/or mathematical ability.

Conditions

Preferred start date is December 1st, 2017 or (very) soon thereafter. The appointment will be initially for a period of 1 year. After satisfactory evaluation of the initial appointment, it can be extended for 3 years (the total duration is 4 years) and should lead to a dissertation (PhD thesis). An educational plan will be drafted that includes attendance to courses and (international) meetings. PhD students are also expected to assist in teaching undergraduates.

You can find information about our excellent fringe benefits of employment www.workingatvu.nl like:
• Remuneration of 8,3% end-of-year bonus and 8% holiday allowance;
• Solid pension scheme (ABP);
• A minimum of 29 holidays in case of full-time employment;
• Generous contribution (65%) commuting allowance based on public transport;

The salary will be in accordance with university regulations for academic personnel, and amounts from € 2.222,00 gross per month in the first year up to
€ 2.840,00 in the fourth year (salary scale 85) based on a full-time employment.

Additional information

Applicants should send a cover letter with their motivation and CV before 5 October 2017 to Natascha Stroo, department manager.

For additional information please contact: Dr. Michel Nivard, m.g.nivard@vu.nl

Any other correspondence in response to this advertisement will not be dealt with.

Bedrijfsomschrijving

Vrije Universiteit Amsterdam (VU) is a leading, innovative and growing university that is at the heart of society and actively contributes to new developments in teaching and research. Our university has ten faculties, and provides work for over 4,500 staff and scientific education for more than 23,000 students.

The Faculty of Behavioural and Movement Sciences (FBM) at VU University Amsterdam is unique in the wide field of behavioural and health sciences for combining the disciplines of psychology, education theory and human movement sciences. The faculty contributes to a better understanding of the way behaviour and movement are caused and can be influenced so as to promote physical and mental health and improve performance.