Atherosclerosis, the underlying cause of the majority of cardiovascular diseases, is a lipid-driven inflammatory disease of the large arteries. Experimental …
PhD student bioinformatics and the origin of eukaryotes (1.0 FTE)
Utrecht University's Faculty of Science has a position available for a PhD student bioinformatics and the origin of eukaryotes. Are you interested? Then please read the full profile and apply.
- Domplein, Utrecht, Utrecht
- Tijdelijk contract / Tijdelijke opdracht
- Uren per week:
- 36 - 40 uur
- € 2222 - € 2840 per maand
You are a PhD student to join our team as part of a project that addresses the origin and ancient evolution of the eukaryotes, funded by a recently awarded NWO VICI grant. The earliest stages of eukaryotic evolution are characterised by a drastic increase in cellular and genomic complexity: already before the last common ancestor of all modern eukaryotes cellular components like the nucleus, cilia, mitochondria, and the elaborate endomembrane system had arisen. You will use our unique in-house collection of eukaryotic genome sequences, some of which have only recently become available, to reconstruct ancestral gene repertoires using bioinformatic techniques. In combination with prokaryotic genome sequences, these repertoires will enable you to elucidate the processes that resulted in the increase in complexity, such as gene and whole-genome duplications, endosymbiosis and horizontal gene transfer.
You, as the ideal candidate, have a background in bioinformatics, data analysis, cell biology, and/or evolutionary biology. You are ambitious, you fit well in our team and you have a strong drive to succeed as a scientist. You will work in a large, dynamic and diverse Computational Biology department. You will be directly supervised by your promotor Prof Berend Snel, and collaborate with two other PhD students and a postdoc within the NWO VICI project.
You will be offered a full-time position for four years. The gross salary is in the range between €2,222 and maximum €2,840 per month for a full-time employment.
The salary is supplemented with a holiday bonus of 8% and an end-of-year bonus of 8.3% per year. In addition we offer: a pension scheme, a partially paid parental leave and flexible employment conditions. The conditions are based on the Collective Labour Agreement Dutch Universities. The research group will provide the candidate with necessary support on all aspects of the project. You’ll find more information about working at Utrecht University here.
Would you like additional information about this vacancy? Then please contact Berend Snel via firstname.lastname@example.org.As part of the selection procedure, you are expected to give an outline of your research plans in a written report and an oral presentation.
A better future for everyone. This ambition motivates our scientists in executing their leading research and inspiring teaching. At Utrecht University, colleagues from various disciplines collaborate intensively towards major societal themes. Our focus is on Dynamics of Youth, Institutions for Open Societies, Life Sciences and Sustainability.
The city of Utrecht is one of the oldest cities in the Netherlands, with a charming old center and an internationally oriented culture that is strongly influenced by its century-old university. Utrecht city has been consistently ranked as one of the most livable cities in the Netherlands.
The Faculty of Science consists of six departments: Biology, Pharmaceutical Sciences, Information and Computing Sciences, Physics and Astronomy, Chemistry and Mathematics. The Faculty is home to 5600 students and nearly 1500 staff and is internationally renowned for the quality of its research. The Faculty's academic programmes reflect developments in today's society. Read the overall impression 2016 of the Faculty of Science.
The Evolutionary Genomics lab at Utrecht University researches the interplay between network and genome evolution by bioinformatic analysis of novel high throughput data and novel genome sequences. By analyzing this interplay we study the predictability of genome evolution, the origins of eukaryotic cellular complexity, and the role of recurrent gene loss and gene duplication in the evolution of cellular processes. In addition to global bioinformatics analyses we study the evolution of individual proteins in collaboration with molecular biology labs at the Science Faculty, the Hubrecht Institute and the UMCU. The evolutionary genomics lab has a leading role in the Utrecht Bioinformatics Center and is embedded within the Theoretical Biology and Bioinformatics group studying various areas in biology with a variety of computational approaches.