The research group Cognitive and Systems Neuroscience of the Swammerdam Institute for Life Sciences (SILS), one of the largest institutes of the Faculty of Science, is looking for a PhD candidate in the field of systems neuroscience, bridging the gap between neurophysiology and human cognition. This project is sponsored by Alzheimer Nederland.
How does the brain form, store and retrieve unique and complex memories?
This project will be supervised by Dr Carien Lansink (Cognitive and Systems Neuroscience Group, SILS-FNWI, UvA). The ability to acquire, store and retrieve information is a fundamental process of human life, as we continuously make decisions and direct our behavior based on previous experiences. Memory disorders, such as Alzheimer’s dementia, affect millions of people worldwide and have a significant physical, emotional, and socio-economic impact. This project will investigate the neurobiological mechanisms of memory processing by neuronal circuitries in healthy individuals and in an Alzheimer’s disease model. Neuronal activity will be recorded using in vivo chronic, multi-area electrophysiology in combination with behavioral tasks testing memory performance. Simultaneously, optogenetic and/ or chemogenetic approaches will be deployed to manipulate neuronal function during task performance. Advanced signal analysis methods will be used to interpret neuronal dynamics in the context of memory processing.
You should have a Master's degree in experimental neuroscience or a related field. Affinity and/or experience in experimental methods for systems neuroscience are a prerequisite. Preferably you have strong programming skills (especially in MATLAB) and experience in developing and applying methods for signal processing and neural data analysis. A certificate for working with laboratory animals (under Dutch legislation) will be an important asset for all these positions. You will also participate in educational activities at the bachelor and/or master levels.
The appointment will be on a temporary basis for a period of 4 years (initial appointment will be for a period of 18 months and after satisfactory evaluation it can be extended to a total duration of 4 years) and should lead to a dissertation (PhD thesis). We will draft an educational plan, including attendance of courses and (international) meetings. You are also expected to assist in teaching of undergraduate students.
Based on a full-time appointment (38 hours per week) the gross monthly salary will range from €2,222 in the first year to €2,840- in the last year. The Collective Labour Agreement of Dutch Universities is applicable. There are also secondary benefits, such as an 8% holiday allowance per year and an end of year allowance of 8.3%.
You may direct inquiries about the positions or any request for additional information to:
Applications may only be submitted by using this link.
Your application must include a curriculum vitae including contact addresses of 2 academic references and a letter of motivation. Please combine these documents in one single attachment.
We will accept applications until 15 July 2018
Interviews will take place from the second half of August ’18.